pentylidene difluoride | 62127-40-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: pentylidene difluoride
• 英文别名: 1,1-difluoropentane
• CAS: 62127-40-6
• 化学式: C₅H₁₀F₂
• 分子量: 108.131
• InChiKey: PSSHQAXMSKKIBE-UHFFFAOYSA-N

物化性质

• 熔点：
  -96.05°C (estimate)
• 沸点：
  86.96°C (rough estimate)
• 密度：
  0.9328 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  pentane-1,1-diyl bis(trifluoromethanesulfonate) 在 1,8-双二甲氨基萘 、 triethylamine tris(hydrogen fluoride) 作用下， 以 二氯甲烷 为溶剂， 反应 5.5h， 生成 pentylidene difluoride
  参考文献：
  名称：

  Preparation of 1,1-difluoroalkanes from aldehydes via 1,1-bistriflates: Advantageous use of HF–Lewis base reagents

  摘要：

  Alkane-1,1-bistriflates, prepared in excellent yields by reaction of aldehydes with triflic anhydride, are converted to their respective 1,1-difluoroalkanes in good to excellent yield through reaction with fluorinating agent, triethylaminetrishydrofluoride. Straight chain 1,1-bistriflates are more reactive than those substituted at the 2-position, but the latter are also converted successfully, without evidence of any rearrangement products. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2014.06.020

文献信息

• The generation of carbon monofluoride (CF) and an investigation of the products of its reaction with alkenes
  作者：M. Rahman、Michael L. McKee、Philip B. Shevlin

  DOI：10.1021/ja00280a029

  日期：1986.10

  La reaction des atomes de C generes a l'arc avec CF 4 en presence d'alcenes comme agents de piegeage conduit a la formation de fluorocyclopropanes et de difluoro-1,1 alcanes. Les fluorocyclopropanes proviennent de l'addition de CF a une double liaison, conduisant a un radical cyclopropyle qui arrache un hydrogene pour donner un cyclopropane. Les difluoro-1,1 alcanes proviendraient d'une reaction de

  La 反应des atomes de Cgeneres a l'arc avec CF 4 en存在d'alcenes comme agent de piegeage导管a la形成氟环丙烷和二氟-1,1烷烃。Les fluorocyclopropanes provinnent de l'addition de CF a une double liaison, conduisant a unradical cyclopropyle qui arrache unhydrone pour donner un cyclopropane。Les difluoro-1,1 alcanes proviendraient d'une 反应 de 3 CF 2
• Preparation of 1,1-difluoroalkanes from aldehydes via 1,1-bistriflates: Advantageous use of HF–Lewis base reagents
  作者：William R. Dolbier、Masamune Okamoto

  DOI：10.1016/j.jfluchem.2014.06.020

  日期：2014.11

  Alkane-1,1-bistriflates, prepared in excellent yields by reaction of aldehydes with triflic anhydride, are converted to their respective 1,1-difluoroalkanes in good to excellent yield through reaction with fluorinating agent, triethylaminetrishydrofluoride. Straight chain 1,1-bistriflates are more reactive than those substituted at the 2-position, but the latter are also converted successfully, without evidence of any rearrangement products. (C) 2014 Elsevier B.V. All rights reserved.