sec-butyldiisopropoxyborane | 86595-33-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硼酸衍生物
• 英文名称: sec-butyldiisopropoxyborane
• 英文别名: butan-2-yl-di(propan-2-yloxy)borane
• CAS: 86595-33-7
• 化学式: C₁₀H₂₃BO₂
• 分子量: 186.102
• InChiKey: XFZIDDFTTVBEMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.12
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  sec-butyldiisopropoxyborane 、 n-己基乙炔基锂 在 盐酸 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以74%的产率得到sec-butyl-1-octynylisopropoxyborane
  参考文献：
  名称：

  有机oboranes。50. -1-基炔基硼酸酯的制备与表征

  摘要：

  DOI：

  10.1021/om00146a032
• 作为产物：
  描述：

  硼酸三异丙酯 在 仲丁基锂 作用下， 生成 sec-butyldiisopropoxyborane
  参考文献：
  名称：

  Process for lithium mono- and diorganylborohydrides

  摘要：

  提供了一种改进的过程，用于从其“醇盐”络合物中解离出硼酸酯，RB（OR'）2和硼烷酸酯，RR'BOR'，不含醇。锂有机硼酸盐LiRB（OR'）3和LiRR'BOR'的热解，其中R是有机基团，R'是直链或支链低级烷基，直接产生相对挥发性的高纯度硼酸酯和硼烷酸酯，留下锂醇盐残留物。用适当的酸卤处理锂有机硼酸盐可以干净地解离出挥发性或非挥发性的硼酸酯或硼烷酸酯，很容易与产生的低级酯副产物分离。还提供了新型化合物锂二甲基硼氢化物。

  公开号：

  US04772751A1

文献信息

• Optically active borinic esters and ketones
  申请人：Aldrich-Boranes, Inc.

  公开号：US04795821A1

  公开（公告）日：1989-01-03

  A process for synthesizing an optically pure ketone comprising the steps of: treating an appropriate optically pure boronic ester with an organolithium compound at -78.degree. C. to obtain the "ate" complex, separating the optically pure borinic ester from the complex and converting said borinic ester into an optically pure ketone represented by the formulae: R*COR.sup.1 and R*COC.tbd.CR.sup.1 wherein R* is a chiral organyl moeity and R.sup.1 is an achiral organyl moeity.

  一种合成光学纯酮的过程，包括以下步骤：在-78℃下用有机锂化合物处理适当的光学纯硼酸酯，以获得“ate”复合物，将光学纯硼酸酯与复合物分离，并将所述硼酸酯转化为由以下公式表示的光学纯酮：R*COR1和R*COC≡CR1，其中R*是手性有机基团，R1是非手性有机基团。
• Improved process for producing pure boronic and borinic esters
  申请人：Aldrich-Boranes, Inc.

  公开号：US04870177A1

  公开（公告）日：1989-09-26

  Improved processes for liberating boronic, RB(OR').sub.2, and borinic, RR'BOR', esters from their "ate" complexes, free of alcohol are provided. Pyrolysis of lithium organylborates LiRB(OR').sub.3 and LiRR'BOR', wherein R is an organyl group and R' is straight or branched-chain lower alkyl, directly yields the relatively volatile boronic and borinic esters in high purity, leaving behind a residue of lithium alkoxide. Treatment of the lithium organylborates with an appropriate acid halide cleanly liberates either volatile or non-volatile boronic or borinic esters, readily separated from the lower alkyl ester produced as a by-product. The novel compound lithium dimethylborohydride is also provided.

  提供了从它们的“ate”配合物中解放出无醇的硼酸酯，RB（OR'）2和硼烷酸酯，RR'BOR'的改进过程。热解锂有机硼酸盐LiRB（OR'）3和LiRR'BOR'，其中R是有机基团，R'是直链或支链低碳链烷基，直接产生相对挥发性的高纯度硼酸酯和硼烷酸酯，留下锂烷氧化物的残留物。用适当的酸卤处理锂有机硼酸盐可以干净地解放出挥发性或非挥发性的硼酸酯或硼烷酸酯，容易与产生的低碳链酯副产物分离。还提供了新型化合物锂二甲基硼氢化物。
• Process for synthesizing lithium mono- and diorganylborohydrides
  申请人：Aldrich-Boranes, Inc.

  公开号：US04870212A1

  公开（公告）日：1989-09-26

  Improved processes for liberating boronic, RB(OR').sub.2, and borinic, RR'BOR', esters from their "ate" complexes, free of alcohol are provided. Pyrolysis of lithium organylborates LiRB(OR').sub.3 and LiRR'BOR', wherein R is an organyl group and R' is straight or branched-chain lower alkyl, directly yields the relatively volatile boronic and borinic esters in high purity, leaving behind a residue of lithium alkoxide. Treatment of the lithium organylborates with an appropriate acid halide cleanly liberates either volatile or non-volatile boronic or borinic esters, readily separated from the lower alkyl ester produced as a by-product. The novel compound lithium dimethylborohydride is also provided.

  提供了一种改进的过程，用于从其“ate”络合物中解放出不含醇的硼酸酯、RB（OR'）2和硼烷酸酯、RR'BOR'。锂有机硼酸盐LiRB（OR'）3和LiRR'BOR'的热解，其中R是有机基团，R'是直链或支链低级烷基，直接产生相对挥发性的高纯度硼酸酯和硼烷酸酯，留下一定量的锂烷氧化物残留物。用适当的酸卤化物处理锂有机硼酸盐可以干净地释放出易挥发或不易挥发的硼酸酯或硼烷酸酯，可以很容易地与产生的低级烷酸酯副产物分离。还提供了一种新的化合物锂二甲基硼氢化物。
• Organoboranes. 56. Systematic study of the reactions of 1-alkenylboronic esters with representative organolithium and Grignard reagents to provide an efficient, selective synthesis of organyl-1-alkenylborinic esters
  作者：Herbert C. Brown、Nagarajan Vasumathi、Navalkishore N. Joshi

  DOI：10.1021/om00028a021

  日期：1993.4

  A selective reaction of the ''ate'' complexes formed with 1-alkenylboronic esters and organolithium or Grignard reagents, by treatment with either Bronsted or Lewis acids at -78-degrees-C to give the corresponding organylalkenylborinic esters, is explored in this study. This systematic, detailed study reveals that the nature of the alkoxy group on boron, the nature and the amount of the alkyllithium or Grignard reagent used, the solvent, the reaction temperature, and the nature and amount of the acid used all play significant roles in influencing both the yield and the selectivity achieved for the formation of the desired organylalkenylborinates. Optimized procedures for the syntheses of representative organylalkenylborinic esters in high yield are summarized.
• Organoboranes. 31. A simple preparation of boronic esters from organolithium reagents and selected trialkoxyboranes
  作者：Herbert C. Brown、Thomas E. Cole

  DOI：10.1021/om50004a009

  日期：1983.10