Methyl 3-chloro-5-fluoro-2-hydroxybenzoate | 4068-74-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methyl 3-chloro-5-fluoro-2-hydroxybenzoate
• CAS: 4068-74-0
• 化学式: C₈H₆ClFO₃
• 分子量: 204.58
• InChiKey: OIOHWYHUDLNJTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines
  申请人：DOWELANCO

  公开号：EP0470669A2

  公开（公告）日：1992-02-12

  Chloro and bromophenols and N-acylanilines are fluorinated in an ortho or para position with an N-fluoropyridinium salt to obtain fluorohalophenols and N-acylfluorohaloanilines, which can be further converted to fluorophenols and N-acylfluoroanilines by reduction. Thus, o-fluorophenol is obtained by fluorination of p-bromophenol with 2-chloro-6-(trichloromethyl)pyridinium fluoroborate and reduction of the product obtained with sodium formate and a palladium catalyst. N-Fluoropyridinium salts having trichloromethyl substituents are disclosed.

  氯代和溴代苯酚及 N-酰基苯胺与 N-氟吡啶鎓盐进行正位或对位氟化反应，可得到氟卤苯酚和 N-酰基氟卤苯胺，再通过还原反应将其转化为氟苯酚和 N-酰基氟苯胺。因此，邻氟苯酚是通过对溴苯酚与 2-氯-6-(三氯甲基)吡啶鎓氟硼酸盐氟化，然后用甲酸钠和钯催化剂还原所得到的产物而得到的。本发明公开了具有三氯甲基取代基的 N-氟吡啶鎓盐。
• US5116982A
  申请人：——

  公开号：US5116982A

  公开（公告）日：1992-05-26
• US5164502A
  申请人：——

  公开号：US5164502A

  公开（公告）日：1992-11-17
• [EN] MESOPOROUS PARTICLES, PREPARATION AND USE THEREOF<br/>[FR] PARTICULES MÉSOPOREUSES, PRÉPARATION ET UTILISATION ASSOCIÉES
  申请人：AGRA GROUP AS

  公开号：WO2014063667A1

  公开（公告）日：2014-05-01

  The invention relates to mesoporous particles containing derivatives of salicylic and jasmonic acids. These particles are suitable for the activation of the induced systemic resistance, systemic acquired resistance, the defence reaction of plants against pathogens and stress, the induction of the production of secondary metabolites and/or the increase of the crop yield and the quality of production. ˙