2'-(4-morpholino)ethyl 2-[4-(5-trifluoromethyl-2-pyridyloxy)phenoxy]propionate | 135730-94-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2'-(4-morpholino)ethyl 2-[4-(5-trifluoromethyl-2-pyridyloxy)phenoxy]propionate
• 英文别名: 2-Morpholin-4-ylethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate
• CAS: 135730-94-8
• 化学式: C₂₁H₂₃F₃N₂O₅
• 分子量: 440.419
• InChiKey: KGOGYBYACQTDLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  70.1
• 氢给体数：
  0
• 氢受体数：
  10

文献信息

• Herbicidal, optically active or racemic substituted propionic acid derivatives, herbicide compositions containing them and process for preparing same
  申请人：ALKALOIDA VEGYESZETI GYAR

  公开号：EP0426491A2

  公开（公告）日：1991-05-08

  The invention relates to novel, herbicidally active 2-[4-(5-trifluoromethyl-2-pyridyloxy)phenoxy]propionic acid derivatives of the general formula (I), wherein A depends on the value of n in such a way that: 1) when n is 0 (zero), A stands for an -NR1R2 substituted amino group, wherein a) R1 stands for hydrogen; R2 means a C1-4alkyl, C2-4alkenyl, C4-7cycloalkyl, heteroaryl-C1-4alkyl group or a -B-NR3R4 group, where B stands for a straight or branched chain C2-4 alkylene group; R3 and R4 are C1-4alkyl groups or R3 and R4 together form an alicyclic group containing 2 to 6 methylene groups and the cycle, when consisting of 6 members, may contain an oxygen or an additional substi tuted or unsubstituted nitrogen in 4-position related to the nitrogen; b) R1 and R2 are different from hydrogen and represent a C1-4alkyl or C2-4alkylene group; or R1 and R2 together form an alicyclic group containing 2-6 methylene groups and the ring, when consisting of 6 members, may contain an oxygen in 4-position related to the nitrogen; 2) when n is other than 0 (zero) (n is 1 or 2), A stands for: a) an -NR5R6 disubstituted amino group, wherein R5 and R6 represent a C1-4alkyl or C2-4alkenyl group; or R5 and R6 together form an alicyclic group containing 2 to 6 methylene groups, and the ring, when consisting of 6 members, may contain an oxygen or an additional substituted or unsubstituted nitrogen in 4-position related to the nitrogen, the alicyclic ring optionally being substituted by one or more methyl group(s); b) or an -O-N = C(CH3)2 group. The invention also relates to herbicide compositions containing the compounds of the general formula (I) as active ingredients as well as to a process for the preparation of these compounds and compositions. The compounds of the general formula (I) selectively kill the monocotyledonous weeds and thus, they can be used for killing monocotyledonous weeds in dicotyledonous cultures.

  该发明涉及一种新颖的除草活性2-[4-(5-三氟甲基-2-吡啶氧基)苯氧基]丙酸衍生物，其一般式为（I），其中A取决于n的值，方式如下：1）当n为0（零）时，A代表一个-NR1R2取代的氨基团，其中a) R1代表氢；R2表示C1-4烷基，C2-4烯基，C4-7环烷基，杂环芳基-C1-4烷基基团或-B-NR3R4基团，其中B代表直链或支链C2-4烷基基团；R3和R4是C1-4烷基基团或R3和R4一起形成含有2至6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧或一个额外取代或未取代的氮原子；b) R1和R2不同于氢，并表示C1-4烷基或C2-4烯基基团；或R1和R2一起形成含有2-6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧；2）当n不为0（零）时（n为1或2），A代表：a) 一个-NR5R6二取代氨基团，其中R5和R6代表C1-4烷基或C2-4烯基基团；或R5和R6一起形成含有2至6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧或一个额外取代或未取代的氮原子，该脂环环可选择性地被一个或多个甲基基团取代；b) 或一个-O-N = C(CH3)2基团。该发明还涉及含有一般式（I）化合物的除草剂组合物作为活性成分，以及制备这些化合物和组合物的过程。一般式（I）化合物选择性杀死单子叶杂草，因此可以用于在双子叶作物中除去单子叶杂草。
• US5199970A
  申请人：——

  公开号：US5199970A

  公开（公告）日：1993-04-06