1-((2,6-dimethylphenyl)thio)propan-2-ol | 55010-06-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1-((2,6-dimethylphenyl)thio)propan-2-ol
• 英文别名: 1-(2,6-Dimethylphenylthio)-2-propanol；1-(2,6-Dimethylphenyl)sulfanylpropan-2-ol；1-(2,6-dimethylphenyl)sulfanylpropan-2-ol
• CAS: 55010-06-5
• 化学式: C₁₁H₁₆OS
• 分子量: 196.313
• InChiKey: URVRDSLAGMNFJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,6-二甲基巯基苯酚 、 methyloxirane 在 BiCl₆^(3-)*2C₄H₁₀N₂*ClH*3H⁽¹⁺⁾*H₂O 作用下， 以 neat (no solvent) 为溶剂， 反应 0.17h， 生成 1-((2,6-dimethylphenyl)thio)propan-2-ol 、 2-(2,6-Dimethylphenyl)sulfanylpropan-1-ol
  参考文献：
  名称：

  An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions

  摘要：

  An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)(2)[Bicl(6)]Cl center dot H2O (1 mol %). This catalyst can be reused several times without significant loss of activity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.10.098

文献信息

• An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions
  作者：Hong-fei Lu、Jun-tao Zhou、He-long Cheng、Lei-lei Sun、Fei-fei Yang、Run-ze Wu、Yu-hua Gao、Zhi-bin Luo

  DOI：10.1016/j.tet.2013.10.098

  日期：2013.12

  An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)(2)[Bicl(6)]Cl center dot H2O (1 mol %). This catalyst can be reused several times without significant loss of activity. (C) 2013 Elsevier Ltd. All rights reserved.