2-Fluorophenyl prop-2-enoate | 89670-69-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 2-Fluorophenyl prop-2-enoate
• 英文别名: (2-fluorophenyl) prop-2-enoate
• CAS: 89670-69-9
• 化学式: C₉H₇FO₂
• 分子量: 166.15
• InChiKey: SJEBUGJRCJZIRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] ANTIESTROGENS FOR CANCER THERAPY<br/>[FR] ANTI-ŒSTROGÈNES DE THÉRAPIE DU CANCER DU SEIN
  申请人：UNIV ILLINOIS

  公开号：WO2018175965A1

  公开（公告）日：2018-09-27

  1, 1-Diarylmethylcycloalkanylidenes are antiestrogens having utility in the treatment of cancer, including recurrent breast cancer and estrogen receptor-positive, endocrine therapy-sensitive tumors or endocrine therapy resistant tumors.

  1,1-二芳基甲基环烷基亚甲基化合物是抗雌激素化合物，在治疗癌症中具有实用价值，包括复发性乳腺癌和雌激素受体阳性、内分泌治疗敏感性肿瘤或内分泌治疗耐药性肿瘤。
• HEPATITIS C VIRUS INHIBITORS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20150376233A1

  公开（公告）日：2015-12-31

  Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

  揭示了具有一般式（I）的丙型肝炎病毒抑制剂。还公开了包含这些化合物的组合物和使用这些化合物抑制HCV的方法。
• Hepatitis C Virus Inhibitors
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20150284409A1

  公开（公告）日：2015-10-08

  Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

  揭示了具有一般公式（I）的丙型肝炎病毒抑制剂。还公开了包含这些化合物的组合物以及使用这些化合物抑制HCV的方法。
• The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier
  申请人：JAPAN SYNTHETIC RUBBER CO., LTD.

  公开号：EP0095932A1

  公开（公告）日：1983-12-07

  A carrier particularly suitable for supporting biological substances is composed of a particulate polymer prepared by polymerizing at least one monomer of formula: (in which R1 and R2 are the same or different and each represents a hydrogen atom or an alkyl group, R3 represents a straight or branched chain alkylene group optionally having a hydroxy substituent, X represents a halogen atom, m is 0 or an integer from 1 to 10 and n is an integer from 1 to 5) optionally in admixture with at least one other copolymerizable monomer. Biological substances which may be supported by the carrier include immunoreactive substances, enzymes, cells and cell-discriminating substances.

  一种特别适用于支持生物物质的载体由至少一种式单体聚合制备的微粒聚合物组成： (其中 R1 和 R2 相同或不同，各自代表氢原子或烷基，R3 代表直链或支链亚烷基，可选择具有羟基取代基，X 代表卤素原子，m 为 0 或 1-10 的整数，n 为 1-5 的整数），可选择与至少一种其它可共聚单体混合。载体可支持的生物物质包括免疫活性物质、酶、细胞和细胞鉴别物质。
• Optical elements comprising polymers of (meth)acrylate esters
  申请人：Hitachi Chemical Co., Ltd.

  公开号：EP0141610A2

  公开（公告）日：1985-05-15

  A polymer obtained by polymerizing tricyclo-[5.2.1.02,6]deca-8-yl acrylate or methacrylate in an amount of 100-5% by weight with one or more copolymerizable unsaturated monomers in an amount of 0 to 95% by weight is excellent in transparency, moisture resistance, and heat resistance and is suitable as a material for optical elements.

  将重量百分比为 100-5%的丙烯酸三环[5.2.1.02,6]癸-8-基酯或甲基丙烯酸酯与重量百分比为 0 至 95%的一种或多种可共聚的不饱和单体聚合而成的聚合物具有优异的透明度、防潮性和耐热性，适合用作光学元件的材料。