3-Amino-5-(aminomethyl)benzamide | 1379361-63-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Amino-5-(aminomethyl)benzamide
• CAS: 1379361-63-3
• 化学式: C₈H₁₁N₃O
• 分子量: 165.19
• InChiKey: QDRRGYKDXABRGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  95.1
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Growth factor binding molecules
  申请人：——

  公开号：US20030118589A1

  公开（公告）日：2003-06-26

  Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.

  生长因子结合分子具有连接到非肽有机支架上的多个肽环，最好是具有四个氨基酸侧链的假六氨基酸肽环。生长因子结合分子能特异性结合各种生长因子，适用于治疗肿瘤或再狭窄。在一个实施方案中，公开了一种血小板衍生生长因子结合分子，用于抑制实体瘤的肿瘤生长和血管生成。
• Growth Factor Binding Molecules
  申请人：Sebti Said

  公开号：US20100210516A1

  公开（公告）日：2010-08-19

  Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.
• US5770380A
  申请人：——

  公开号：US5770380A

  公开（公告）日：1998-06-23
• US7157419B2
  申请人：——

  公开号：US7157419B2

  公开（公告）日：2007-01-02
• US7632805B2
  申请人：——

  公开号：US7632805B2

  公开（公告）日：2009-12-15