fluorenone-2,6-dicarboxylic acid | 60505-55-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: fluorenone-2,6-dicarboxylic acid
• 英文别名: 2,6-dicarboxyfluorenone；2,6-dicarboxyfluorenon；9H-Fluorene-2,6-dicarboxylic acid, 9-oxo-；9-oxofluorene-2,6-dicarboxylic acid
• CAS: 60505-55-7
• 化学式: C₁₅H₈O₅
• 分子量: 268.226
• InChiKey: ZWAQUZWFYDYXDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-(9H-芴-3-基)-乙酮 、 fluorenone-2,6-dicarboxylic acid 生成 2,6-Diacetylfluorene
  参考文献：
  名称：

  Cyclic carbonyl compounds

  摘要：

  某些氟酮和蒽醌化合物，每个化合物都通过一个羧基或盐、酯或可选择的取代酰胺2-取代，并且每个化合物在5、6、7或8位置可选择地通过第二个羧基，盐、酯或可选择的取代酰胺进行取代，氟酮化合物的5、6、7或8位置的取代基还可以选择自氰基、卤素、硝基、烷基、烷氧基和酰基，对于缓解或预防过敏症状是有用的。

  公开号：

  US03987088A1
• 作为产物：
  描述：

  biphenyl-2,4′,5-tricarboxylic acid 在 硫酸 作用下， 以95%的产率得到fluorenone-2,6-dicarboxylic acid
  参考文献：
  名称：

  A Practical Synthesis of 2,6-Dicarboxyfluorenone

  摘要：

  在此，我们报告了一种新的高效方法，用于大规模合成2,6-二甲基荧光酮5，产率达95%。该方法使用0.01摩尔%的双（三苯基膦）钯(II)氯化物[(PPh3)2 PdCl2]作为催化剂，反应以2,5-二甲基溴苯与4-溴甲苯反应生成2,4,5-三甲基联苯3，随后进行氧化和环化。

  DOI：

  10.1039/a805065a

文献信息

• Optimized liquid-phase oxidation
  申请人：Wonders George Alan

  公开号：US20060047145A1

  公开（公告）日：2006-03-02

  Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process.

  公开了一种优化的工艺和装置，用于更有效和经济地进行可氧化化合物的液相氧化。这种液相氧化是在气泡柱反应器中进行的，可以在相对较低的温度下提供高效的反应。当被氧化的化合物是对二甲苯，氧化反应的产物是粗对苯二甲酸（CTA）时，这种CTA产物可以通过比传统高温氧化工艺更经济的技术进行纯化和分离。
• Process for the oxidative purification of terephthalic acid
  申请人：——

  公开号：US20040110981A1

  公开（公告）日：2004-06-10

  Disclosed is a process to produce a purified carboxylic acid slurry. The process comprises removing impurities from a crystallized product in a solid liquid displacement zone to form the purified carboxylic acid slurry. The purified carboxylic acid slurry is further cooled in a cooling zone and subsequently filtered and dried in a filtration and drying zone. The process produces purified carboxylic acid product having good color and low impurity levels without the use of purification steps like hydrogenation or filtrate purge.

  本发明公开了一种生产纯化羧酸浆的方法。该方法包括在固液置换区从结晶产品中去除杂质，以形成纯化羧酸浆。纯化羧酸浆在冷却区进一步冷却，随后在过滤和干燥区过滤和干燥。该方法生产出具有良好颜色和低杂质水平的纯化羧酸产品，无需使用氢化或过滤液净化等纯化步骤。
• Processes for producing terephthalic acid
  申请人：Sumner Edwan Charles

  公开号：US20060205977A1

  公开（公告）日：2006-09-14

  Processes for producing terephthalic acid are disclosed, the processes comprising combining in a reaction medium p-xylene, a solvent comprising water and one or more saturated organic acids having from 2-4 carbon atoms, and an oxygen-containing gas, at a temperature from about 135° C. to about 165° C., in the presence of a catalyst composition comprising cobalt atoms and manganese atoms, with bromine atoms provided as a promoter. The amount of cobalt used may be from about 1,800 ppm to about 6,000 ppm, with respect to the total weight of the liquid in the reaction medium, and the weight ratio of cobalt to manganese may be from about 40 to about 400. The processes according to the invention produce terephthalic acid as a precipitated reaction product, with typically no more than about 10 ppm 2,6-dicarboxyfluorenone produced, with respect to the weight of the terephthalic acid produced, or no more than about 20 ppm 2,6-dicarboxyfluorenone, with respect to the total weight of the reaction medium, per batch or upon one pass through a reactor. The terephthalic acid so produced may be further purified by one or more additional oxidation reactions, without the need for expensive hydrogenation purification processes.

  公开了生产对苯二甲酸的工艺，该工艺包括在反应介质中混合p-二甲苯、包含水和一个或多个具有2-4个碳原子的饱和有机酸的溶剂以及含氧气体，在存在钴原子和锰原子的催化剂组合物的情况下，以溴原子作为促进剂，在温度约为135℃至165℃之间进行。使用的钴量可以是相对于反应介质中液体的总重量约为1,800 ppm至6,000 ppm，而钴与锰的重量比可以是约40至400。本发明的工艺产生沉淀的对苯二甲酸作为反应产物，通常不会产生超过约10 ppm的2,6-二羧基芴酮，相对于所产生的对苯二甲酸的重量，或不超过约20 ppm的2,6-二羧基芴酮，相对于反应介质的总重量，每批次或通过反应器的一次通行。因此生产的对苯二甲酸可以通过一个或多个附加的氧化反应进一步纯化，而无需昂贵的氢化纯化工艺。
• [EN] PRODUCTION OF AROMATIC CARBOXYLIC ACIDS<br/>[FR] PRODUCTION D'ACIDES CARBOXYLIQUES AROMATIQUES
  申请人：DU PONT

  公开号：WO2002006201A1

  公开（公告）日：2002-01-24

  A process for the production of an aromatic carboxylic acid comprising contacting in the presence of a catalyst, within a continuous flow reactor, one or more precursors of the aromatic carboxylic acid with an oxidant, such contact being effected with said precursor(s) and the oxidant in an aqueous solvent comprising water under supercritical conditions or near supercritical conditions close to the supercritical point such that said one or more precursors, oxidant and aqueous solvent constitute a substantially single homogeneous phase in the reaction zone, wherein the contact of at least part of said precursor with said oxidant is contemporaneous with contact of said catalyst with at least part of said oxidant.

  一种生产芳香羧酸的工艺，包括在连续流反应器中，在催化剂的存在下，将一种或多种芳香羧酸前体物与氧化剂接触，所述接触是在水的超临界条件或接近超临界条件的水溶剂中进行的，使得所述一种或多种前体物、氧化剂和水溶剂在反应区域中构成一个基本单一的均相相位，其中至少部分前体物与氧化剂的接触与至少部分催化剂与氧化剂的接触同时发生。
• Visible light absorbing peroxy esters
  申请人：LOCTITE CORPORATION

  公开号：EP0147226A2

  公开（公告）日：1985-07-03

  Compounds represented by the formula: wherein R1 is alkyl, aralkyl, alkoxyalkyl, alkenyl, alkynyl, carboxyalkyl or carboxyaryl; R2 is any group which does not cause spontaneous decomposition of the peroxy group; and x and y are integers between 0 and 4 with x + y great than or equal to 1, are disclosed. The inventive compounds are useful as visible and UV photoinitiators and as thermal or chemical initiators for curing compositions of ethylenically unsaturated monomers and prepolymers.

  由式表示的化合物： 其中 R1 是烷基、芳基、烷氧基烷基、烯基、炔基、羧基烷基或羧基芳基；R2 是不会引起过氧基团自发分解的任何基团；x 和 y 是 0 至 4 之间的整数，x + y 大于或等于 1。 本发明化合物可用作可见光和紫外线光引发剂，以及用于固化乙烯基不饱和单体和预聚物组合物的热引发剂或化学引发剂。