4-fluoro-2-pentyl-phenol | 451-20-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-fluoro-2-pentyl-phenol
• 英文别名: 5-Fluor-2-hydroxy-1-pentyl-benzol；4-Fluor-2-pentyl-phenol；4-Fluoro-2-pentylphenol
• CAS: 451-20-7
• 化学式: C₁₁H₁₅FO
• 分子量: 182.238
• InChiKey: NLEIWFBVKHXZAP-UHFFFAOYSA-N

物化性质

• 沸点：
  104.5-105.5 °C
• 密度：
  1.041 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-fluoro-2-pentyl-phenol 、 sodium monochloroacetic acid 在 sodium hydroxide 作用下， 生成 (4-fluoro-2-pentyl-phenoxy)-acetic acid
  参考文献：
  名称：

  The Synthesis and Germicidal Properties of Some Alkylfluorophenols

  摘要：

  DOI：

  10.1021/ja01870a052
• 作为产物：
  描述：

  4-fluoro-2-pentyl-phenetole 在 氢碘酸 、 溶剂黄146 作用下， 生成 4-fluoro-2-pentyl-phenol
  参考文献：
  名称：

  The Synthesis and Germicidal Properties of Some Alkylfluorophenols

  摘要：

  DOI：

  10.1021/ja01870a052

文献信息

• Preparation of fluorophenols
  申请人：SHARP & DOHME INC

  公开号：US02334229A1

  公开（公告）日：1943-11-16
• LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER
  申请人：Chemtura Corporation

  公开号：EP2459576A1

  公开（公告）日：2012-06-06
• MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
  申请人：CS Pharmasciences, Inc.

  公开号：US20160214996A1

  公开（公告）日：2016-07-28

  The compounds and salts of the present invention inhibit kinases, especially the anaplastic lymphoma kinase (ALK) and the HGF receptor tyrosine kinase (RTK) c-Met, and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
• [EN] DISINTEGRANT COMPOSITION<br/>[FR] COMPOSITION DELITANTE
  申请人：FMC CORP

  公开号：WO2002050231A1

  公开（公告）日：2002-06-27

  Disintegrant granules and compressed detergent tablets or bodies made therefrom are disclosed. More paticularly, the disintegrant granules comprise low-lignin cellulose particles, such as Kraft or sulfite woodpulp and/or microcrystalline cellulose, in combination with a cross-linked disintegrant such as cross-linked carboxymethylcellulose, crospovidone, a cross-linked polyacrylate, or a mixture of two or more of these cross-linked materials, the disintegrant granules exhibit high water absorptivity and swellability and produce compressed detergent tablets with low friability. The detergent tablets dissolve rapidly in aqueous media, such as that found in conventional laundry or dishwashing cycles.
• [EN] LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER<br/>[FR] COMPOSITIONS LIQUIDES DE TRISARYL PHOSPHITES ALKYLÉS AYANT DEUX GROUPES ALKYLE AVEC DES NOMBRES DE CARBONE DIFFÉRENTS
  申请人：CHEMTURA CORP

  公开号：WO2011014477A1

  公开（公告）日：2011-02-03

  A composition comprising a mixture of at least two different alkylaryl phosphites, wherein some alkyl groups have a different number of carbon atoms than other alkyl groups and wherein the mixture is a liquid at ambient conditions.