methyl-2 dithia-1,4 cyclohexene-2 | 5769-49-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: methyl-2 dithia-1,4 cyclohexene-2
• 英文别名: 5-methyl-2,3-dihydro-1,4-dithiin；5-methyl-2,3-dihydro-[1,4]dithiine；2,3-dihydro-5-methyl-1,4-dithiin；2-Methyl-5,6-dihydro-<1,4>-dithion；2-Methyl-5,6-dihydro-1,4-dithiin；5-Methyl-2,3-dihydro-1,4-dithiine
• CAS: 5769-49-3
• 化学式: C₅H₈S₂
• 分子量: 132.251
• InChiKey: XRCNPRZPSUNYAI-UHFFFAOYSA-N

物化性质

• 沸点：
  73-74 °C
• 密度：
  1.133±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(2-丙炔基硫代)乙醇 在 sodium hydroxide 、 三溴化磷 、 对苯二酚 作用下， 以 吡啶 、 乙醇 、 水 为溶剂， 反应 27.0h， 生成 methyl-2 dithia-1,4 cyclohexene-2
  参考文献：
  名称：

  Dupuy, Claude; Surzur, Jean-Marie, Bulletin de la Societe Chimique de France, 1980, vol. 2, # 7-8, p. 353 - 360

  摘要：

  DOI：

文献信息

• Synthesis of 2,3-Dihydro-1,4-dithiins and 2-Alkylidene-1,4-dithianes by 1,2-Sulfur Migration in 2-(1-Hydroxyalkyl)-1,3-dithiolanes
  作者：Carlos A. M. Afonso、M. Teresa Barros、Licio S. Godinho、Christopher D. Maycock

  DOI：10.1055/s-1991-26520

  日期：——

  2,3-Dihydro-1,4-dithiins and the isomeric 2-alkylidene-1,4-dithianes were synthesized from 1,2-diketones and alkyl pyruvates by kinetically controlled ring expansion of 2-(1-hydroxyalkyl)-1,3-dithiolanes with p-toluenesulfonyl chloride in pyridine. In addition, 2,3-dihydro-1,4-dithiins, the thermodynamic products, were formed exclusively by using p-toluenesulfonic acid in refluxing benzene. The 2-alkylidene-1,4-dithianes were readily isomerised to the corresponding 2,3-dihydro-1,4-dithiins. Similarly, 2,3-dimethyl-6, 7-dihydro-5H-1,4-dithiepine and (+)-2-methylene-3-methyl-1,4-dithiepane were obtained from 2-[(S)-1-hydroxyethyl]-2-methyl-1,3-dithiane.

  2,3-二氢-1,4-二硫烯和异构的2-烷基烯-1,4-二硫烷是通过在吡啶中用对甲苯磺酰氯对2-(1-羟基烷基)-1,3-二硫烷进行动力学控制的环扩展，从1,2-二酮和烷基丙酮酸酯合成的。此外，使用对甲苯磺酸在回流苯中，可以专门形成热力学产物2,3-二氢-1,4-二硫烯。2-烷基烯-1,4-二硫烷可轻易异构化为相应的2,3-二氢-1,4-二硫烯。同样，2,3-二甲基-6,7-二氢-5H-1,4-二硫哌啶和(+)-2-亚甲基-3-甲基-1,4-二硫烷是由2-[(S)-1-羟基乙基]-2-甲基-1,3-二硫烷得到的。
• Synthesis of Sulfur-containing Heterocycles by Thermolysis of a-Alkylthio-N-aziridinylimines
  作者：Sunggak Kim、Chang Mook Cho

  DOI：10.3987/com-94-6816

  日期：——

  Thermolysis of alpha-alkylthio substituted N-aziridinylimines in refluxing toluene gave various structurally different sulfur-containing heterocycles in high yields.
• Sukhai, R. S.; Jong, R. de; Verkruijsse, H. D., Recueil des Travaux Chimiques des Pays-Bas, 1981, vol. 100, # 10, p. 368 - 372
  作者：Sukhai, R. S.、Jong, R. de、Verkruijsse, H. D.、Brandsma, L.

  DOI：——

  日期：——
• Stereoselective azide introduction during 1,2-sulfur migration in α-hydroxyalkyldithioacetals
  作者：Carlos A.M. Afonso、M.Teresa Barros、Christopher D. Maycock

  DOI：10.1016/s0040-4020(98)01072-2

  日期：1999.1

  A series alpha-hydroxyalkyldithiolanes were reacted with a mixture of triphenylphosphine, diethyl azodicarboxylate and hydrazoic acid to give 2-azido-1,4-dithianes stereoselectively. Reduction of the azido group to an amine resulted in racemisation. (C) 1998 Elsevier Science Ltd. All rights reserved.
• Dupuy, Claude; Crozet, Michel-Pierre; Surzur, Jean-Marie, Bulletin de la Societe Chimique de France, 1980, vol. 2, # 7-8, p. 361 - 373
  作者：Dupuy, Claude、Crozet, Michel-Pierre、Surzur, Jean-Marie

  DOI：——

  日期：——