2-Methylpropanoic acid pentafluorobenzyl ester | 21634-98-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Methylpropanoic acid pentafluorobenzyl ester
• 英文别名: pentafluorobenzyl ester of isobutyric acid；(2,3,4,5,6-Pentafluorophenyl)methyl 2-methylpropanoate；(2,3,4,5,6-pentafluorophenyl)methyl 2-methylpropanoate
• CAS: 21634-98-0
• 化学式: C₁₁H₉F₅O₂
• 分子量: 268.183
• InChiKey: DZHXAKOYPKOEDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  五氟苯甲醇 、 异丁酸 在 potassium carbonate 作用下， 以 甲醇 为溶剂， 反应 3.0h， 生成 2-Methylpropanoic acid pentafluorobenzyl ester
  参考文献：
  名称：

  Selective Determination of Pentafluorobenzyl Ester Derivatives of Carboxylic Acids by GC Using Microwave Plasma and Mass Selective Detection

  摘要：

  已开发出一种基于氟选择性气相色谱（GC）检测五氟苯甲酸酯衍生物的高度选择性、敏感的水中羧酸测定方法。大气压氦微波诱导等离子体检测器非常适合氟特异性检测这些衍生物，这些衍生物通过毛细管GC得到很好的分辨，并在GC-质谱选择性检测时表现出特征性的碎裂行为。为了演示目的，检测了一系列从C1到C20的羧酸，并发现它们的衍生产率大于90％，并对一份小溪水样品进行了羧酸含量检测。

  DOI：

  10.1366/0003702914335193

文献信息

• SUBSTITUTED IMIDAZOLES
  申请人：CHUBB NATHAN ANTHONY LOGAN

  公开号：US20080125473A1

  公开（公告）日：2008-05-29

  This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.

  本发明涉及一系列α取代的2-苯甲基取代咪唑化合物及其药学上可接受的盐和溶剂化物，包括含有这种化合物的组合物，它们的合成过程以及它们作为寄生虫药物的用途。
• SENSOR
  申请人：FUJIFILM Corporation

  公开号：EP3660486A1

  公开（公告）日：2020-06-03

  The present invention provides a sensor having excellent sensitivity and selectivity with respect to a ketone-based compound. This sensor according to the present invention has a receiving layer including a polymer having a repeating unit represented by Formula (1), and detects a ketone-based compound.

  本发明提供了一种对酮基化合物具有极佳灵敏度和选择性的传感器。根据本发明，这种传感器具有一个接收层，接收层包括具有由式（1）表示的重复单元的聚合物，该接收层可检测酮基化合物。
• Biosynthesis of methacrylic acid and isobutyric acids in a carabid beetle, Scarites subterraneus
  作者：Athula B. Attygalle、Jerrold Meinwald、Thomas Eisner

  DOI：10.1016/s0040-4039(00)93477-4

  日期：1991.9

  D8-L-Valine is incorporated with high efficiency into methacrylic and isobutyric acids in the pygidial defensive glands of a carabid beetle, Scarites subterraneus.
• US7547718B2
  申请人：——

  公开号：US7547718B2

  公开（公告）日：2009-06-16
• Selective Determination of Pentafluorobenzyl Ester Derivatives of Carboxylic Acids by GC Using Microwave Plasma and Mass Selective Detection
  作者：Jeffrey H. Brill、Bikshandarkoil A. Narayanan、John P. McCormick

  DOI：10.1366/0003702914335193

  日期：1991.12

  A highly selective, sensitive method for determination of carboxylic acids in water has been developed that is based on fluorine-selective gas chromatography (GC) detection of pentafluorobenzyl ester derivatives. The atmospheric-pressure helium microwave-induced plasma detector is well suited for fluorine-specific detection of these derivatives, which were well resolved by capillary GC and displayed a characteristic fragmentation behavior when examined by GC-mass selective detection. For demonstration purposes, a number of carboxylic acids, ranging from C₁ to C₂₀, were examined and found to be derivatized with yields greater than 90%, and a sample of creek water was examined for its carboxylic acid content.

  已开发出一种基于氟选择性气相色谱（GC）检测五氟苯甲酸酯衍生物的高度选择性、敏感的水中羧酸测定方法。大气压氦微波诱导等离子体检测器非常适合氟特异性检测这些衍生物，这些衍生物通过毛细管GC得到很好的分辨，并在GC-质谱选择性检测时表现出特征性的碎裂行为。为了演示目的，检测了一系列从C1到C20的羧酸，并发现它们的衍生产率大于90％，并对一份小溪水样品进行了羧酸含量检测。