6-Bromo-2-octyl-1,3-benzothiazole | 1323977-97-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 6-Bromo-2-octyl-1,3-benzothiazole
• 英文别名: 6-bromo-2-octyl-1,3-benzothiazole
• CAS: 1323977-97-4
• 化学式: C₁₅H₂₀BrNS
• 分子量: 326.301
• InChiKey: OTCBKKYKTLTURT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  41.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  壬醛 、 2-氨基苯硫醇 在 吡啶 、 三溴化锑 、 phenyltrimethylammonium tribromide 作用下， 以 二氯甲烷 为溶剂， 反应 37.0h， 以49%的产率得到6-Bromo-2-octyl-1,3-benzothiazole
  参考文献：
  名称：

  Regioselective One-Pot Synthesis of 2-Aryl-6-bromobenzothiazole from Arylaldehyde and 2-Aminothiophenol with Phenyltrimethylammonium Tribromide in the Presence of a Catalytic Amount of Antimony(III) Bromide

  摘要：

  Various 2-aryl-6-bromo-1,3-benzothiazoles were regioselectively afforded in good yields by the reaction of arylaldehydes and 2-aminothiophenol with phenyltrimethylammonium tribromide in the presence of a catalytic amount of SbBr(3) in CH(2)Cl(2) at room temperature.

  DOI：

  10.3987/com-11-12178

文献信息

• Regioselective One-Pot Synthesis of 2-Aryl-6-bromobenzothiazole from Arylaldehyde and 2-Aminothiophenol with Phenyltrimethylammonium Tribromide in the Presence of a Catalytic Amount of Antimony(III) Bromide
  作者：Shinsei Sayama

  DOI：10.3987/com-11-12178

  日期：——

  Various 2-aryl-6-bromo-1,3-benzothiazoles were regioselectively afforded in good yields by the reaction of arylaldehydes and 2-aminothiophenol with phenyltrimethylammonium tribromide in the presence of a catalytic amount of SbBr(3) in CH(2)Cl(2) at room temperature.