1,3-Bis(hydroxymethyl)-4-methylimidazolidin-2-one | 2492-96-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 1,3-Bis(hydroxymethyl)-4-methylimidazolidin-2-one
• CAS: 2492-96-8
• 化学式: C₆H₁₂N₂O₃
• 分子量: 160.17
• InChiKey: UBHXVADGCTXVOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  64
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS
  申请人：BASF SE

  公开号：US20200190052A1

  公开（公告）日：2020-06-18

  The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

  该发明主要涉及一种调制方法，优选是体外和/或体内调制寒冷薄荷醇受体TRPM8的方法，其中受体与本文描述的结构类型1的化合物群中至少一种调制剂接触。本发明还涉及相关用途和包含这些化合物的组合物。
• LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF
  申请人：BASF SE

  公开号：US20170265510A1

  公开（公告）日：2017-09-21

  The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.

  本发明涉及新型的冷薄荷感受受体TRPM8的调制剂，以及利用这些调制剂调节TRPM8受体的方法；特别是利用这些调制剂诱导寒冷感觉的用途；以及利用这些调制剂生产的文章和组合物。
• Reactive polysaccharide derivatives, their preparation and their use
  申请人：Hall-Goulle Veronique

  公开号：US20070113356A1

  公开（公告）日：2007-05-24

  A reactive polysaccharide derivative of formula (1 a ) or (1 b ), in which A is —O—, —S— or (1 c ), Q 1 is hydrogen, the radical —B—A—Z, C 1 -C 10 aryl which is unsubstituted or substituted, C 1 -C 12 alkyl which may be interrupted by oxygen and is unsubstituted or substituted, Q 2 and Q 3 are each independently of the other hydrogen, C 1 -C 12 aryl which is unsubstituted or substituted, C 1 -C 12 alkyl which may be interrupted by oxygen and is unsubstituted or substituted, B is an aliphatic or aromatic bridge member, Z 1 and Z 2 are each independently of the other a reactive radical of the vinylsulfonyl series, the haloacryloyl series or the heterocyclic series, PS is a polysaccharide radical, m is 0, 1 or an integer greater than 1, n is 1 or an integer greater than 1, and the sum of n+m corresponds to the original number of hydroxy groups in the polysaccharide molecule, is useful as a finishing agent for textile fibers and for other applications.

  公式（1a）或（1b）的反应性多糖衍生物，其中 A 是—O—、—S—或（1c），Q1 是氢、基团—B—A—Z、未取代或取代的 C1-C10 芳基、未取代或取代的 C1-C12 烷基，其中可以通过氧原子中断，Q2 和 Q3 各自独立地是氢、未取代或取代的 C1-C12 芳基、未取代或取代的 C1-C12 烷基，其中可以通过氧原子中断，B 是脂肪族或芳香族桥接成员，Z1 和 Z2 各自独立地是乙烯基磺酰基系列、卤代丙烯酰基系列或杂环系列的反应性基团，PS 是多糖基团，m 是 0、1 或大于 1 的整数，n 是 1 或大于 1 的整数，n+m 的和对应于多糖分子中的羟基原子数，可用作纺织纤维的整理剂和其他应用。
• Thermoplastic resin film laminate and production thereof
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP0172269A2

  公开（公告）日：1986-02-26

  A thermoplastic resin film laminate which comprises a thermoplastic resin film, particularly, a polyester film and a layer of a polyester resin composition provided on at least one surface of the film, said composition comprising (A) a water insoluble polyester copolymer composed of a mixed dicarboxylic acid component containing a dicarboxylic acid having metal sulfonate group in an amount of 0.5 to 15 mol % based on all the dicarboxylic acid component and a glycol component; and (B) inert particles; the weight ratio of (A)/(B)=100,000/0.5-3,000. Optionally, the composition can contain one or more ingredients selected from the group consisting of a water soluble silicone, a polyfunctional reactive compound, a polyethylene glycol and its derivative and an antistatic agent. The thermoplastic resin film laminate is preferably produced by so-called in-line coating.

  一种热塑性树脂薄膜层压制品，包括热塑性树脂薄膜，特别是聚酯薄膜，以及在薄膜至少一个表面上提供的一层聚酯树脂组合物，所述组合物包括 (A) 不溶于水的聚酯共聚物，由混合二羧酸组分和乙二醇组分组成，混合二羧酸组分含有金属磺酸基的二羧酸，其含量为所有二羧酸组分的 0.5 至 15 摩尔%；以及 (B) 惰性颗粒；(A)/(B)的重量比=100,000/0.5-3,000。可选地，该组合物可以包含一种或多种选自水溶性硅酮、多官能团反应化合物、聚乙二醇及其衍生物和抗静电剂的成分。热塑性树脂薄膜层压板最好采用所谓的在线涂覆法生产。
• POLYESTER FILM BEING EASY TO ADHERE TO INK RECEIVING LAYER
  申请人：Teijin Dupont Films Japan Limited

  公开号：EP1426404A1

  公开（公告）日：2004-06-09

  A polyester adhesive film readily adhering to an ink-receiving layer comprising a coating layer having a surface energy of 54 to 70 dyne/cm and a polyester film containing an ultraviolet light absorber, wherein at least one surface of the polyester film is coated with the coating layer. Accordingly, there is provided the polyester adhesive film readily adhering to an ink-receiving layer, having excellent adhesiveness to an ink-receiving layer, excellent transparency and weatherability and useful as image-receiving paper and the like for ink jet printers.

  一种易于粘附到受墨层的聚酯粘合膜，包括表面能量为 54 至 70 达因/厘米的涂层和含有紫外线吸收剂的聚酯薄膜，其中聚酯薄膜的至少一个表面涂有涂层。 因此，本发明提供了易于粘附到受墨层的聚酯胶膜，该胶膜与受墨层的粘附性极佳，具有极佳的透明度和耐候性，可用作喷墨打印机的图像接收纸等。