4-[(Butan-2-yl)amino]benzaldehydato | 27914-23-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[(Butan-2-yl)amino]benzaldehydato
• 英文别名: 4-(butan-2-ylamino)benzaldehyde
• CAS: 27914-23-4
• 化学式: C₁₁H₁₅NO
• 分子量: 177.24
• InChiKey: NZETVQZHPCRDIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Method for producing tryptamine derivatives
  申请人：——

  公开号：US20030096379A1

  公开（公告）日：2003-05-22

  The invention relates to a coupled enzymatic process for producing tryptamine derivatives from indole compounds. In the first enzyme-catalyzed reaction, indole derivatives are converted to tryptophan derivative intermediates, then the tryptophan intermediates are decarboxylated in a second enzymatic reaction in the same reaction system. In this way, tryptamine derivative products are formed from indole derivatives in a single process. The invention is also directed to novel tryptophan and tryptamine derivatives, which can be prepared by the inventive method.

  本发明涉及一种从吲哚化合物中生产色胺衍生物的耦合酶促反应过程。在第一次酶催化反应中，吲哚衍生物被转化为色氨酸衍生物中间体，然后在同一反应体系中进行第二次酶催化反应，将色氨酸中间体脱羧。这样，通过单一过程从吲哚衍生物中形成色胺衍生物产品。该发明还涉及新型色氨酸和色胺衍生物，可以通过本发明方法制备。
• [EN] METHOD FOR PRODUCING TRYPTAMINE DERIVATIVES<br/>[FR] PROCEDE DE PRODUCTION DE DERIVES DE TRYPTAMINE
  申请人：BIOCATALYTICS INC

  公开号：WO2002079153A1

  公开（公告）日：2002-10-10

  The invention relates to a coupled enzymatic process for producing tryptamine derivatives from indole compounds. In the first enzyme-catalyzed reaction, indole derivatives are converted to tryptophan derivative intermediates, then the tryptophan intermediates are decarboxylated in a second enzymatic reaction in the same reaction system. In this way, tryptamine derivative products are formed from indole derivatives in a single process. The invention is also directed to novel tryptophan and tryptamine derivatives, which can be prepared by the inventive method.