5-Beta-胆甾烷-3-beta, 6-beta-二醇 | 570-86-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 5-Beta-胆甾烷-3-beta, 6-beta-二醇
• 中文别名: 5-Beta-胆甾烷-3-beta,6-beta-二醇
• 英文名称: 5β-cholestane-3β,6β-diol
• 英文别名: 5β-cholestanediol-(3β.6β)；(10R)-3c.6c-Dihydroxy-10r.13c-dimethyl-17c-((R)-1.5-dimethyl-hexyl)-(5cH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren；3β.6β-Dihydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-6β-gonan；5β-Cholestandiol-(3β.6β)；coprostane-3β,6β-diol；5α-Cholestan-3β,6β-diol；(3beta,5beta,6beta)-Cholestane-3,6-diol；(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol
• CAS: 570-86-5
• 化学式: C₂₇H₄₈O₂
• 分子量: 404.677
• InChiKey: PMWTYEQRXYIMND-YHMDZATGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-Beta-胆甾烷-3-beta, 6-beta-二醇 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 5β-Cholestane-3,6-dione
  参考文献：
  名称：

  The Fate of Hydrogen Peroxide as an Oxygen Source for Bioremediation Activities within Saturated Aquifer Systems

  摘要：

  In situ bioremediation is an innovative technique for the remediation of contaminated aquifers that involves the use of microorganisms to remediate soils and groundwaters polluted by hazardous substances. During its application, this process may require the addition of nutrients and/or electron accepters to stimulate appropriate biological activity. Hydrogen peroxide has been commonly used as an oxygen source because of the Limited concentrations of oxygen that can be transferred into the groundwater using above-ground aeration followed by reinjection of the oxygenated groundwater into the aquifer or subsurface air sparging of the aquifer. Because of several potential interactions of H2O2 with various aquifer material constituents, its decomposition may be too rapid, making effective introduction of the H2O2 into targeted treatment zones extremely difficult and costly. Therefore, a bench-scale study was conducted to determine the fate of H2O2 within subsurface aquifer environments. The purpose of this investigation was to identify those aquifer constituents, both biotic and abiotic, that are most active in controlling the fate of H2O2. The decomposition rates of H2O2 were determined using both equilibrated water samples and soil slurries. Results showed H2O2 decomposition to be effected by several commonly found inorganic soil components; however, biologically mediated catalytic reactions were determined to be the most substantial.

  DOI：

  10.1080/10473289.2000.10464207
• 作为产物：
  描述：

  cholesterol 在 氢氧化钾 作用下， 生成 5-Beta-胆甾烷-3-beta, 6-beta-二醇
  参考文献：
  名称：

  The Hydration of Unsaturated Steroids by the Brown Hydroboration Reaction. I. Monounsaturated Steroids

  摘要：

  DOI：

  10.1021/jo01028a032

文献信息

• Meiosis regulating compounds
  申请人：——

  公开号：US20030032824A1

  公开（公告）日：2003-02-13

  Certain compounds, structurally related to natural compounds which can be extracted i.a. from bull testes and from human follicular fluid, can be used for regulating the meiosis in oocytes and in male germ cells. Some of these compounds are useful in the treatment of infertility, whereas other compounds are useful as contraceptives. These compounds have the structural formula 1 wherein the substituents are as defined in the specification.

  某些化合物与天然化合物结构相关，可以从公牛睾丸和人类卵泡液中提取，用于调节卵母细胞和雄性生殖细胞的减数分裂。其中一些化合物在不孕症治疗中很有用，而其他化合物则可用作避孕药。这些化合物具有结构式1，其中取代基如规范中所定义。
• Biellmann,J.-F.; Johnson,W.S., Bulletin de la Societe Chimique de France, 1965, p. 3500 - 3506
  作者：Biellmann,J.-F.、Johnson,W.S.

  DOI：——

  日期：——
• Holland, Herbert L.; Khan, Saeed R., Canadian Journal of Chemistry, 1985, vol. 63, p. 2763 - 2768
  作者：Holland, Herbert L.、Khan, Saeed R.

  DOI：——

  日期：——
• The Hydration of Unsaturated Steroids by the Brown Hydroboration Reaction. I. Monounsaturated Steroids
  作者：Manasse Nussim、Yehuda Mazur、Franz Sondheimer

  DOI：10.1021/jo01028a032

  日期：1964.5
• The Fate of Hydrogen Peroxide as an Oxygen Source for Bioremediation Activities within Saturated Aquifer Systems
  作者：Mark Zappi、Kenneth White、Huey-Min Hwang、Rakesh Bajpai、Mohammad Qasim

  DOI：10.1080/10473289.2000.10464207

  日期：2000.10

  In situ bioremediation is an innovative technique for the remediation of contaminated aquifers that involves the use of microorganisms to remediate soils and groundwaters polluted by hazardous substances. During its application, this process may require the addition of nutrients and/or electron accepters to stimulate appropriate biological activity. Hydrogen peroxide has been commonly used as an oxygen source because of the Limited concentrations of oxygen that can be transferred into the groundwater using above-ground aeration followed by reinjection of the oxygenated groundwater into the aquifer or subsurface air sparging of the aquifer. Because of several potential interactions of H2O2 with various aquifer material constituents, its decomposition may be too rapid, making effective introduction of the H2O2 into targeted treatment zones extremely difficult and costly. Therefore, a bench-scale study was conducted to determine the fate of H2O2 within subsurface aquifer environments. The purpose of this investigation was to identify those aquifer constituents, both biotic and abiotic, that are most active in controlling the fate of H2O2. The decomposition rates of H2O2 were determined using both equilibrated water samples and soil slurries. Results showed H2O2 decomposition to be effected by several commonly found inorganic soil components; however, biologically mediated catalytic reactions were determined to be the most substantial.