3-((4-nitrophenyl)thio)phenol | 103863-18-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3-((4-nitrophenyl)thio)phenol
• 英文别名: 3-(4-nitro-phenylsulfanyl)-phenol；3-(4-Nitro-phenylmercapto)-phenol；3-(4-Nitrophenyl)sulfanylphenol；3-(4-nitrophenyl)sulfanylphenol
• CAS: 103863-18-9
• 化学式: C₁₂H₉NO₃S
• 分子量: 247.274
• InChiKey: IAWUPSXNWVTVOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-(4-硝基-苯基硫烷基)-苯胺 在 sodium nitrite 作用下， 生成 3-((4-nitrophenyl)thio)phenol
  参考文献：
  名称：

  Leandri; Tundo, Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1956, vol. 14, p. 31

  摘要：

  DOI：

文献信息

• Copper Mediated Formation of Carbon-Heteroatom Bonds Using Organoboron Reagents and Ultrasound
  作者：George W. Kabalka、Bryan J. Musolino

  DOI：10.3987/com-14-s(k)18

  日期：——

  This report summarizes research efforts focused on copper acetate mediated reactions to form new carbon-heteroatom bonds using organoboron reagents under ultrasound irradiation. The method involves the application of ultrasound irradiation to the Chan-Evans-Lam reaction to achieve O-arylation of phenols, N-arylation of anilines and indoles, and S-arylation of thiols. Ultrasound irradiation was found to decrease reaction times from 72 hours to 4 hours while improving the product yields an average of 20%(1) Representative C-O, C-N, and C-S coupling reactions were successfully scaled-up from the milligram to gram levels while maintaining good product yields offering potential applications in industrial processes.
• Leandri; Tundo, Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1956, vol. 14, p. 31
  作者：Leandri、Tundo

  DOI：——

  日期：——