9-oxa-bicyclo[ 15.1.0]octadecan-8-one | 942117-26-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 9-oxa-bicyclo[ 15.1.0]octadecan-8-one
• 英文别名: 9-Oxa-bicyclo[15.1.0]octadecan-8-one；9-oxabicyclo[15.1.0]octadecan-8-one
• CAS: 942117-26-2
• 化学式: C₁₇H₃₀O₂
• 分子量: 266.424
• InChiKey: XCTWNXUGCBIJQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (9E)-oxacycloheptadec-9-en-2-one 、 二碘甲烷 在 锌铜偶 、 碘 作用下， 以 乙醚 为溶剂， 以8.1%的产率得到9-oxa-bicyclo[ 15.1.0]octadecan-8-one
  参考文献：
  名称：

  Cyclopropanated macrocyclic ketones and lactones

  摘要：

  本发明涉及一种新颖的环丙基化的大环酮和内酯化合物，其一般化学式为其中X是从0、N、S、CH或CH2组成的原子或官能团；Y是由1至20个碳原子组成的直链或支链碳氢基团；W是由1至20个碳原子组成的直链或支链碳氢基团；O是氧原子；以及这些新颖化合物在制造香水、古龙香水和个人护理产品等物品中的用途。

  公开号：

  US20060234883A1

文献信息

• Cyclopropanated Macrocyclic Ketones and Lactones
  申请人：Narula Anubhav P.S.

  公开号：US20090087402A1

  公开（公告）日：2009-04-02

  The present invention is directed to novel cyclopropanated macrocyclic ketone and lactone compounds of the general formula: wherein X is an atom or a functional group selected from the group consisting of O, N, S, R—CH, and CH2; wherein R is a C1-C3 alkyl group; wherein Y and W independently represent is a linear or branched alkyl or alkenyl group, optionally substituted, consisting of less than 10 and preferably less than 7 carbon atoms; and wherein O is an oxygen atom, and the use of these novel compounds in creating fragrances and scents in items such as perfumes, colognes, and personal care products.

  本发明涉及新的环丙基化的大环酮和内酯化合物，其一般式如下：其中X为从O、N、S、R—CH和CH2组成的群体中选取的原子或官能团；其中R为C1-C3烷基；其中Y和W分别表示线性或支链烷基或烯基，可选地取代，由少于10个碳原子组成，优选少于7个碳原子；并且O为氧原子。这些新化合物在创造香水、古龙香水和个人护理产品等物品的香味和气味方面有用。
• Cyclopropanated macrocyclic lactone
  申请人：International Flavors & Fragrances Inc.

  公开号：EP2301927A1

  公开（公告）日：2011-03-30

  The present invention is directed to a cyclopropanated macrocyclic lactone compound of the formula and the use of this compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products.

  本发明涉及一种式如下的环丙烷化大环内酯化合物 以及该化合物在香水、古龙水和个人护理产品等产品中制造香料和香味的用途。
• Cyclopropanated macrocyclic ketone
  申请人：International Flavors & Fragrances, Inc.

  公开号：EP1712538B1

  公开（公告）日：2011-07-27
• CYCLOPROPANATED MACROCYCLIC KETONES AND LACTONES
  申请人：Narula Anubhav P.S.

  公开号：US20090081150A1

  公开（公告）日：2009-03-26

  The present invention is directed to novel cyclopropanated macrocyclic ketone and lactone compounds of the general formula: wherein X is an atom or a functional group selected from the group consisting of O, N, S, R—CH, and CH2; wherein R is a C1-C3 alkyl group; wherein Y and W independently represent is a linear or branched alkyl or alkenyl group, optionally substituted, consisting of less than 10 and preferably less than 7 carbon atoms; and wherein O is an oxygen atom, and the use of these novel compounds in creating fragrances and scents in items such as perfumes, colognes, and personal care products.
• US7189881B2
  申请人：——

  公开号：US7189881B2

  公开（公告）日：2007-03-13