4-Phenyl-3-carbethoxy-phenol | 34265-59-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Phenyl-3-carbethoxy-phenol
• 英文别名: Ethyl p-hydroxybiphenylcarboxylate；ethyl 5-hydroxy-2-phenylbenzoate
• CAS: 34265-59-3
• 化学式: C₁₅H₁₄O₃
• 分子量: 242.274
• InChiKey: SLHSDOYNPALHAO-UHFFFAOYSA-N

物化性质

• 沸点：
  422.2±33.0 °C(Predicted)
• 密度：
  1.167±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-Phenyl-3-carbethoxy-phenol 在 硫酸 作用下， 生成 2-羟基-9-芴
  参考文献：
  名称：

  Migration of electronegative substituents. I. Relative migratory aptitude and migration tendency of the carbethoxy group in the dienone-phenol rearrangement

  摘要：

  DOI：

  10.1021/ja00814a022
• 作为产物：
  描述：

  4-oxo-1-phenyl-2,5-cyclohexadiene-1-carboxylic acid ethyl ester 在 三氟乙酸 作用下， 生成 4-Phenyl-3-carbethoxy-phenol
  参考文献：
  名称：

  Migration of electronegative substituents. I. Relative migratory aptitude and migration tendency of the carbethoxy group in the dienone-phenol rearrangement

  摘要：

  DOI：

  10.1021/ja00814a022

文献信息

• Mesomorphic compound, liquid crystal composition and liquid crystal
  申请人：Canon Kabushiki Kaisha

  公开号：US05690858A1

  公开（公告）日：1997-11-25

  A mesomorphic compound represented by the following formula (I): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 independently denote methyl group or a mesomorphic residual group, at least one of R.sub.1, R.sub.2 and R.sub.3 being a mesomorphic residual group having an optically active group of the formula below as a terminal flexible group: ##STR2## wherein R.sub.4 is an alkyl group having 1-12 carbon atoms; n is an integer of 0-10; m is an integer of 1-10; and L is an integer of 1-100. The mesomorphic compound is usable for constituting a liquid crystal composition and a liquid crystal device having a large picture area and capable of showing an improved switching characteristic and a good impact resistance.

  以下是用中文翻译的结果： 一种由以下式子（I）表示的介向化合物：##STR1## 其中R.sub.1、R.sub.2和R.sub.3独立地表示甲基基团或介向残基基团，其中至少有一个R.sub.1、R.sub.2或R.sub.3是具有下述式子中的光学活性基团作为末端柔性基团的介向残基基团：##STR2## 其中R.sub.4是具有1-12个碳原子的烷基基团；n是0-10的整数；m是1-10的整数；L是1-100的整数。该介向化合物可用于构成具有大画面区域、能够显示改善的开关特性和良好冲击抗性的液晶组合物和液晶器件。
• Mesomorphic compound, liquid crystal composition and liquid crystal device
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0599289A1

  公开（公告）日：1994-06-01

  A mesomorphic compound represented by the following formula (I): wherein R₁, R₂ and R₃ independently denote methyl group or a mesomorphic residual group, at least one of R₁, R₂ and R₃ being a mesomorphic residual group having an optically active group of the formula below as a terminal flexible group: wherein R₄ is an alkyl group having 1 - 12 carbon atoms; n is an integer of 0 - 10; m is an integer of 1 - 10; and L is an integer of 1 - 100. The mesomorphic compound is usable for constituting a liquid crystal composition and a liquid crystal device having a large picture area and capable of showing an improved switching characteristic and a good impact resistance.

  下式(I)所代表的中间体化合物： 其中 R₁、R₂ 和 R₃ 独立地表示甲基或介形残基，R₁、R₂ 和 R₃ 中至少有一个是介形残基，其末端柔性基团为下式中的光学活性基团： 其中 R₄ 是具有 1-12 个碳原子的烷基；n 是 0-10 的整数；m 是 1-10 的整数；L 是 1-100 的整数。该介晶化合物可用于构成液晶组合物和液晶器件，该液晶组合物和液晶器件的图像面积大，能显示出更好的开关特性和良好的抗冲击性。
• Oxygenative and Dehydrogenative [3 + 3] Benzannulation Reactions of α,β-Unsaturated Aldehydes and γ-Phosphonyl Crotonates Mediated by Air: Regioselective Synthesis of 4-Hydroxybiaryl-2-carboxylates
  作者：Prabhakar Ramchandra Joshi、Jagadeesh Babu Nanubolu、Rajeev S. Menon

  DOI：10.1021/acs.orglett.6b00016

  日期：2016.2.19

  Regioselective synthesis of 4-hydroxybiphenyl-2-carboxylates via the base-mediated oxygenative [3 + 3] benzannulation reaction of alpha,beta-unsaturated aldehydes and gamma-phosphonyl crotonates is reported. A hydroxyl group is installed in the final product on the originally phosphorus-bound carbon via a novel oxygenative and dehydrogenative transformation. The reaction proceeds rapidly in an open flask, uses atmospheric oxygen as an oxidant, and affords good yields of substituted biaryl phenols.
• US5462695A
  申请人：——

  公开号：US5462695A

  公开（公告）日：1995-10-31
• US5690858A
  申请人：——

  公开号：US5690858A

  公开（公告）日：1997-11-25