di(2,3-dimethylphenyl) carbazone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: di(2,3-dimethylphenyl) carbazone
• 英文别名: N',2-Bis(2,3-dimethylphenyl)diazenecarbohydrazide；1-(2,3-dimethylanilino)-3-(2,3-dimethylphenyl)iminourea
• 化学式: C₁₇H₂₀N₄O
• 分子量: 296.372
• InChiKey: MYDVWQBOZMNHAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  bis(2,3-Dimethylphenyl) carbohydrazide 在 盐酸 、 ferric nitrate 作用下， 以 乙酸乙酯 为溶剂， 反应 0.08h， 以90%的产率得到di(2,3-dimethylphenyl) carbazone
  参考文献：
  名称：

  一种制备二芳基碳腙的高效固相法

  摘要：

  摘要 首次报道了固相法制备二芳基卡巴腙。使用 Fe(NO3)3.9H2O 作为氧化剂，在温和的条件下以优异的产率合成了七种二芳基碳腙。该方法方便有效。

  DOI：

  10.1080/00397910008087170

文献信息

• An Efficient and Convenient Procedure for Preparation of Diaryl Carbazone from aryl substituted carbazide
  作者：Yulu Wang、Lei Shi、Xueshun Jia、Feng Pan、Donglan Ma、Xiaoyang Wang

  DOI：10.1080/00397919908085734

  日期：1999.1.1

  A new facile method for the synthesis of diaryl carbazone (ArN=NCONHNHAr) from aryl substituted carbazide is described. Eight of the compounds were preparated by oxidation of aryl substituted carbazide with ferric chloride in acid medium at room tempreture in good yield.
• Li, Xiao-Chuan; Wang, Yu-Lu; Wang, Jin-Ye, Journal of Chemical Research - Part S, 2002, # 5, p. 234 - 235
  作者：Li, Xiao-Chuan、Wang, Yu-Lu、Wang, Jin-Ye

  DOI：——

  日期：——
• SELECTIVE AND EFFICIENT OXIDATION OF DIARYL CARBAZIDE TO DIARYL CARBAZONE WITH NaNO₂–ACETIC ANHYDRIDE UNDER MILD CONDITIONS
  作者：Xiao-Chuan Li、Yu-Lu Wang、Jin-Ye Wang

  DOI：10.1081/scc-120014033

  日期：2002.1

  In this paper, ten diaryl carbazide undergo selective and rapid oxidation to the corresponding diaryl carbazone using NaNO2 -acetic anhydride as a novel oxidant under mild conditions for the first time.
• Rapid Synthesis of Diaryl Carbazone by N-Bromosuccinimide and Pyridine as the Oxidation System
  作者：Yu-Lu Wang、Zhi-Fang Duan、Lti Shi、Xiao-Yang Wang、Jian-Ping Li

  DOI：10.1080/00397919908085784

  日期：1999.2

  A new and rapid synthetic method of diaryl carbazone (ArN=NCONHNHAr) from aryl substituted carbazide is reported for the first time. Eight of the compounds were prepared by oxidation of aryl substituted carbazide using N-Bromosuccinimide and pyridine as the oxidation system in good yield under mild condition. This method only need simple instrument and short reaction time. A possible mechanism is suggested.
• SOLID STATE SELECTIVE SYNTHESIS OF DIARYL CARBAZONE
  作者：Jun-Ping Xiao、Yu-Lu Wang、Qing-Xiang Zhou

  DOI：10.1081/scc-100103253

  日期：2001.1

  The selective synthesis of diaryl carbazone using K3Fe(CN)(6), as oxidant under alkaline condition in solid state is reported for the first time. Eight diaryl carbazone have been synthesized in excellent yields, and this method only needs cheap reagents, and simple procedure under mild condition.