2-Phenethyl-isothiourea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Phenethyl-isothiourea
• 英文别名: 2-phenylethyl carbamimidothioate
• 化学式: C₉H₁₂N₂S
• 分子量: 180.27
• InChiKey: BQDZMSRPNHLCMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  75.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  苯那地平杂质9 、 2-Phenethyl-isothiourea 生成 methyl 6-methyl-4-(3-nitrophenyl)-2-(2-phenylethylsulfanyl)-1,4-dihydropyrimidine-5-carboxylate
  参考文献：
  名称：

  KURONO, MASATSUNEH;XAYASI, MOTOXIDEH;MIURA, KEHNSI;ISOKAVA, KOGAKU;SAVAI,+

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING BISPHENOL COMPOUND
  申请人：Tsutsuminai Susumu

  公开号：US20120010434A1

  公开（公告）日：2012-01-12

  Provided is a process for producing a bisphenol compound stably at a high conversion and with high selectivity over a long period. A process for producing a bisphenol compound by feeding a phenol compound and a carbonyl compound continuously to a reactor packed with an acid catalyst, characterized in that the acid catalyst is a sulfonic-acid-form cation-exchange resin in which part of the sulfo groups have been modified with at least any one of 2-pyridylalkanethiol compounds and 3-pyridylalkanethiol compounds.

  提供一种稳定地以高转化率和高选择性长时间生产双酚化合物的方法。通过将苯酚化合物和羰基化合物连续加入装有酸性催化剂的反应器来生产双酚化合物的方法，其特征在于所述酸性催化剂是一种磺酸基离子交换树脂，其中部分磺酸基已被2-吡啶基烷硫醇化合物和3-吡啶基烷硫醇化合物之一修饰。
• CANNABINOID RECEPTOR MEDIATING COMPOUNDS
  申请人：The United States of America, as represented by the Secretary, Department of Health and Human Serv

  公开号：US20160257654A1

  公开（公告）日：2016-09-08

  A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB 1 receptor mediating scaffold and (ii) a second therapeutic scaffold.

  一种化合物，或其药学上可接受的盐或酯，包括（i）CB1受体介导的支架和（ii）第二个治疗支架。
• Cannabinoid receptor mediating compounds
  申请人：The United States of America, as represented by the Secretary, Department of Health and Human Services

  公开号：US10683270B2

  公开（公告）日：2020-06-16

  A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold.

  一种化合物或其药学上可接受的盐或酯，包含(i)与(ii)第二治疗支架共轭的 CB1 受体介导支架。
• Cannabinoid receptor mediating iminopyrazole compounds
  申请人：The United States of America, as represented by the Secretary, Department of Health and Human Services

  公开号：US10787419B2

  公开（公告）日：2020-09-29

  A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold.

  一种化合物或其药学上可接受的盐或酯，包含(i)与(ii)第二治疗支架共轭的 CB1 受体介导支架。
• US4208430A
  申请人：——

  公开号：US4208430A

  公开（公告）日：1980-06-17