3-(triphenyl-λ5-phosphanyl)propanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(triphenyl-λ5-phosphanyl)propanoic acid
• 化学式: C₂₁H₂₁O₂P
• 分子量: 336.4
• InChiKey: ADLGMIFSXLCREI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide.
  申请人：Sathe Dhananjay Govind

  公开号：US20100009977A1

  公开（公告）日：2010-01-14

  Disclosed herein is an improved process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide (Brinzolamide) and novel intermediates thereof.

  本文披露了一种改进的工艺，用于制备(R)-(+)-4-(乙基氨基)-3,4-二氢-2-(3-甲氧基丙基)-2H-噻吩[3,2-e]-1,2-噻嗪-6-磺酰胺-1,1-二氧化物（布林唑胺）及其新颖的中间体。
• [EN] SUBSTITUTED PYRIMIDINES AND TRIAZINES AS HERBICIDES<br/>[FR] PYRIMIDINES ET TRIAZINES SUBSTITUÉES UTILISÉES EN TANT QU'HERBICIDES
  申请人：FMC CORP

  公开号：WO2021183980A1

  公开（公告）日：2021-09-16

  Disclosed are compounds of Formula I, stereoisomers, TV-oxides, and salts thereof, wherein; A is selected from A-2, A-2, A-3, A-4, A-5, A-6, A-7, A-8, A-9 and A-10 and A, A-l, A-2, A-3, A-4, A-5, A-6, A-7, A-8, A-9, A-10, R1 through R20b, W, X and Y are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

  公开的是Formula I的化合物，立体异构体，TV-氧化物及其盐，其中；A从A-2，A-2，A-3，A-4，A-5，A-6，A-7，A-8，A-9和A-10中选择，A，A-l，A-2，A-3，A-4，A-5，A-6，A-7，A-8，A-9，A-10，R1到R20b，W，X和Y如披露中定义。还公开了含有Formula I化合物的组合物以及用于控制不受欢迎植被的方法，包括将不受欢迎的植被或其环境与本发明的化合物或组合物的有效量接触。
• Kinase antagonists
  申请人：Knight A. Zachary

  公开号：US20070293516A1

  公开（公告）日：2007-12-20

  The present invention provides novel compounds that are antagonists of PI3 kinase, PI3 kinase and tryosine kinase, PI3Kinase and mTOR, or PI3Kinase, mTOR and tryosine kinase.

  本发明提供了一种新型化合物，它们是 PI3 激酶、PI3 激酶和酪氨酸激酶、PI3 激酶和 mTOR，或者 PI3 激酶、mTOR 和酪氨酸激酶的拮抗剂。
• GPR120 RECEPTOR AGONISTS AND USES THEREOF
  申请人：Shi Dong Fang

  公开号：US20110313003A1

  公开（公告）日：2011-12-22

  GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.

  提供了GPR120激动剂。这些化合物对于治疗代谢性疾病非常有用，包括II型糖尿病和与血糖控制不佳有关的疾病。
• 4-Substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same
  申请人：Davies M. L. Huw

  公开号：US20070004787A1

  公开（公告）日：2007-01-04

  Disclosed are 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles. Also disclosed are methods for making 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles, including those having the formulae. The methods include contacting a 4-substituted-6,7-dihydro indole, benzofuran, benzothiophene, benzimidazole, benzoxazole, or benzothiazole compound or a 7-substituted-4,5-dihydro indole, benzofuran, benzothiophene, benzimidazole, benzoxazole, or benzothiazole compound with a vinyldiazo compound in the presence of a dirhodium catalyst.

  揭示了4-取代和7-取代的吲哚、苯并呋喃、苯并噻吩、苯并咪唑、苯并噁唑和苯并噻唑。还揭示了制备4-取代和7-取代的吲哚、苯并呋喃、苯并噻吩、苯并咪唑、苯并噁唑和苯并噻唑的方法，包括具有下列式的化合物。该方法包括在双铑催化剂存在下将4-取代-6,7-二氢吲哚、苯并呋喃、苯并噻吩、苯并咪唑、苯并噁唑或苯并噻唑化合物或7-取代-4,5-二氢吲哚、苯并呋喃、苯并噻吩、苯并咪唑、苯并噁唑或苯并噻唑化合物与乙烯双重氮化合物接触。