1-(2-Bromoethyl)pyridin-1-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(2-Bromoethyl)pyridin-1-ium
• 化学式: C7H9BrN+
• mdl: MFCD01073004
• 分子量: 187.06
• InChiKey: IZNLVYVGSDBDMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• [EN] PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS<br/>[FR] PYRIDINE-2-AMIDES UTILES COMME AGONISTES DE CB2
  申请人：HOFFMANN LA ROCHE

  公开号：WO2014086806A1

  公开（公告）日：2014-06-12

  The invention relates to CB2 agonists of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

  这项发明涉及到公式（I）中的CB2激动剂，其中R1至R4的定义如描述和索赔中所述。公式（I）的化合物可用作药物。
• [EN] NOVEL PYRIDINE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS DE PYRIDINE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2014086705A1

  公开（公告）日：2014-06-12

  The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

  该发明涉及一种化合物，其化学式为（I），其中R1至R3的定义如描述和索赔中所述。化合物的化学式（I）可用作药物。
• Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms
  申请人：TFCHEM

  公开号：US10100088B2

  公开（公告）日：2018-10-16

  The present invention relates to a compound of the following formula (I): in which at least one and only one group chosen among R5, R6 and R7 is a group of the following formula: The present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermatological applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermatological compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.

  本发明涉及以下式（I）的化合物： 其中R5、R6和R7中至少一个且仅有一个基团选择为以下式的基团： 本发明还涉及该化合物的用途，用于生物材料和/或微生物的保存和/或保护和/或再生以及用于化妆品或皮肤学应用，如抗衰老、皮肤保护和皮肤再生；包含这种化合物的培养、储存和/或保存培养基；包含这种化合物的化妆品或皮肤学组合物；制备这种化合物的方法；以及合成中间体。
• [EN] THERAPEUTIC COMPOUNDS<br/>[FR] COMPOSÉS THÉRAPEUTIQUES
  申请人：GILEAD SCIENCES INC

  公开号：WO2015130964A1

  公开（公告）日：2015-09-03

  Compounds of Formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, intermediates useful for preparing compounds of Formula I and therapeutic, methods for treating a Retroviridae viral infection, in particular infection caused by the HIV virus.

  公式I的化合物或其盐已被披露。还披露了包含公式I化合物的药物组合物，制备公式I化合物的方法，用于制备公式I化合物的中间体以及治疗Retroviridae病毒感染的治疗方法，特别是HIV病毒引起的感染。
• [EN] 5,6-DISUBSTITUTED PYRIDINE-2-CARBOXAMIDES AS CANNABINOID RECEPTOR AGONISTS<br/>[FR] PYRIDINE-2-CARBOXAMIDES BISUBSTITUÉS EN 5,6 SERVANT D'AGONISTES DU RÉCEPTEUR CANNABINOÏDE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2015150438A1

  公开（公告）日：2015-10-08

  The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) are agonists of the Cannabinoid Receptor 2 and are therefore useful in the treatment of various diseases such as pain, atherosclerosis, inflammation etc.

  该发明涉及公式（I）的化合物，其中R1至R4的定义如描述和索赔中所述。公式（I）的化合物是大麻素受体2的激动剂，因此在治疗各种疾病如疼痛、动脉硬化、炎症等方面具有用处。