4-(Acetyloxy)-alpha-ethenyl-3-methoxybenzenemethanol acetate | 52946-23-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 4-(Acetyloxy)-alpha-ethenyl-3-methoxybenzenemethanol acetate
• 英文别名: [4-[(1S)-1-acetyloxyprop-2-enyl]-2-methoxyphenyl] acetate
• CAS: 52946-23-3
• 化学式: C₁₄H₁₆O₅
• 分子量: 264.27
• InChiKey: NKRBAUXTIWONOV-LBPRGKRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• FLAVOR COMPOSITION CONTAINING FLAVONE GLYCOSIDES
  申请人：Bardsley Kathryn

  公开号：US20120251465A1

  公开（公告）日：2012-10-04

  The present invention has discovered that flavone glycosides represented by Formula I set forth below have unexpected and advantageous flavor enhancement and modification properties: wherein R 1 is selected from the group consisting of H and CH 3 , R 2 is selected from the group consisting of H and OH, and R 3 is a 7-O-glycoside. Thus, the flavone glycosides of the present invention can be used to enhance or modify the flavor of orally consumable compositions, such as foodstuff, chewing gums, dental and oral hygiene products, and medicinal products.

  本发明发现了以下公式I所表示的黄酮苷具有意外和优越的口味增强和修改特性：其中R1选择自H和CH3的群组，R2选择自H和OH的群组，R3是7-O-糖苷。因此，本发明的黄酮苷可用于增强或修改口服组合物的口味，如食品、口香糖、口腔卫生产品和药品。
• FLAVOUR MODULATING SUBSTANCES
  申请人：Winkel Chris

  公开号：US20100129515A1

  公开（公告）日：2010-05-27

  The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, tobacco products and oral care products, using a flavour modulating substance selected from the group represented by formula (I), edible salts thereof and edible esters thereof. It has been found that these substances are capable imparting highly desirable taste attributes in the products they are incorporated in. In addition said flavour modulating substances are capable of modulating and complementing, the sensory impact of other, taste imparting, substances. Thus, the present substances are advantageously applied in flavour compositions, foodstuffs, tobacco products and oral care products. Typical examples of flavour modulating substances according to the present invention include N-vanillyl urea, N-vanillyl thiourea, N-vanillyl guanidine, N-isovanillyl urea, N-(3-ethoxy-4-hydroxybenzyl) urea, N-(3,4 dimethoxybenzyl) urea, N,N′-divanillyl urea, N,N′-divanillyl thiourea, N-octyl-N′-vanillyl urea, N-octyl-N′-vanillyl thiourea, N-hexyl-N′-vanillyl urea, N-hexyl-N′-vanillyl thiourea, N-decyl-N′-vanillyl urea, N-decyl-N′-vanillyl thiourea, N-benzyl-N′-vanillyl urea, N-benzyl-N′-vanillyl thiourea, edible salts thereof and edible esters thereof.

  本发明在第一方面涉及使用从式(I)所代表的化合物组中选择的调味调节物质、其可食用盐和可食用酯，对食品、饮料、烟草制品和口腔护理产品中的味道进行调节。已经发现这些物质能够在它们被加入的产品中赋予高度可取的口感特性。此外，所述调味调节物质能够调节和补充其他具有口感影响的物质的感官影响。因此，本发明的物质优点地应用于调味组合物、食品、烟草制品和口腔护理产品中。根据本发明的典型的调味调节物质包括N-香草基尿素，N-香草基硫脲，N-香草基胍，N-异香草基尿素，N-(3-乙氧基-4-羟基苯基)尿素，N-(3,4-二甲氧基苯基)尿素，N,N'-二香草基尿素，N,N'-二香草基硫脲，N-辛基-N'-香草基尿素，N-辛基-N'-香草基硫脲，N-己基-N'-香草基尿素，N-己基-N'-香草基硫脲，N-癸基-N'-香草基尿素，N-癸基-N'-香草基硫脲，N-苄基-N'-香草基尿素，N-苄基-N'-香草基硫脲，其可食用盐和可食用酯。
• Flavor composition containing flavone glycosides
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP2505075A1

  公开（公告）日：2012-10-03

  The present invention has discovered that flavone glycosides represented by Formula I set forth below have unexpected and advantageous flavor enhancement and modification properties: wherein R1 is selected from the group consisting of H and CH3, R2 is selected from the group consisting of H and OH, and R3 is a 7-O-glycoside. Thus, the flavone glycosides of the present invention can be used to enhance or modify the flavor of orally consumable compositions, such as foodstuff, chewing gums, dental and oral hygiene products, and medicinal products.

  本发明发现，由下述式 I 所代表的黄酮苷具有意想不到的增香和改香特性： 其中 R1 选自 H 和 CH3 组成的组，R2 选自 H 和 OH 组成的组，R3 是 7-O 糖苷。因此，本发明的黄酮苷可用于增强或改变口服组合物的风味，如食品、口香糖、牙科和口腔卫生产品以及医药产品。
• 1'-Acetoxychavicol acetate for tuberculosis treatment
  申请人：National Science and Technology Development Agency

  公开号：US20020192262A1

  公开（公告）日：2002-12-19

  1′-Acetoxychavicol acetate is a compound not known before to possess anti-tuberculous activity. The above data revealed that the compound was active against the standard H37Ra strain as well as several clinical isolates at the concentration well below the toxic concentration against various mammalian cells. The compound is therefore potentially useful as an therapeutic and preventive agent for tuberculosis as well as an antiseptic agent against the bacteria.

  1′-Acetoxychavicol acetate 是一种以前不知道具有抗结核活性的化合物。上述数据表明，该化合物对标准 H37Ra 菌株和几种临床分离株具有活性，其浓度远远低于对各种哺乳动物细胞的毒性浓度。因此，该化合物具有治疗和预防结核病的潜在作用，也是一种抗菌剂。
• Novel synergistic compositions containing aromatic compounds and terpenoids present in Alpinia galanga
  申请人：Enrovita A/S

  公开号：US20030157204A1

  公开（公告）日：2003-08-21

  Novel compositions of matter containing aromatic compounds and terpenoids which are present in and may preferably be derived from the plant Alpinia galanga (Zingiberaceae) show synergistic effects with respect to immunomodulation, and they significantly suppress hypersensitivity reactions. Thus they are used for preparing medicaments for these purposes and, more specifically, for the treatment or prevention of IgE mediated allergic reactions and conditions, such as asthma, allergic rhinitis, atopic eczema or anaphylaxis, and autoimmune disorders, such as Crohn's disease, ulcerative colitis, rheumatoid arthritis or psoriasis, as well as for the alleviation of pain. They can for example be formulated into pharmaceuticals, cosmetics or dietary supplements. A method of preparing such compositions from Alpinia galanga is also described.

  含有芳香族化合物和萜类化合物的新型物质组合物，这些化合物和萜类化合物存在于以下植物中，最好可以从这些植物中提取 高良姜 (Zingiberaceae)中的芳香族化合物和萜类化合物的新型物质组合物在免疫调节方面具有协同作用，并能显著抑制超敏反应。因此，它们可用于配制上述用途的药物，更具体地说，可用于治疗或预防 IgE 介导的过敏反应和病症，如哮喘、过敏性鼻炎、特应性湿疹或过敏性休克，以及自身免疫性疾病，如克罗恩病、溃疡性结肠炎、类风湿性关节炎或牛皮癣，还可用于减轻疼痛。例如，它们可以配制成药品、化妆品或膳食补充剂。从以下植物中制备此类成分的方法 高良姜 的制备方法。