Aniline, 4-tert-butyl-3-methyl- | 129373-05-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Aniline, 4-tert-butyl-3-methyl-
• 英文别名: 4-tert-butyl-3-methylaniline
• CAS: 129373-05-3
• 化学式: C₁₁H₁₇N
• 分子量: 163.26
• InChiKey: VNVLJLMYRJMAOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PYRAZOLOQUINOLINONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
  申请人：BENAZET ALEXANDRE

  公开号：US20130079337A1

  公开（公告）日：2013-03-28

  The invention relates to compounds corresponding to formula (I) in which R1, R2 and R3 are as defined in Claim 1 , and also to the process for preparing them and to their therapeutic use.

  这项发明涉及与式（I）相对应的化合物，其中R1、R2和R3如权利要求1中所定义的，并且还涉及制备它们的过程以及它们的治疗用途。
• BROAD-SPECTRUM NON-COVALENT CORONAVIRUS PROTEASE INHIBITORS
  申请人：Purdue Research Foundation

  公开号：US20170313685A1

  公开（公告）日：2017-11-02

  This invention pertains to materials and methods for the treatment of patients with coronavirus infection and the control of zoonotic disease outbreaks using broad-spectrum non-covalent coronavirus protease inhibitors.

  这项发明涉及利用广谱非共价冠状病毒蛋白酶抑制剂治疗冠状病毒感染患者以及控制人畜共患病爆发的材料和方法。
• Isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof
  申请人：KANGPU BIOPHARMACEUTICALS, LTD.

  公开号：US10017492B2

  公开（公告）日：2018-07-10

  Provided are an isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof. The isoindoline derivative and the pharmaceutical composition thereof can regulate the production or activity of immunological cytokines, thus effectively treating cancer and inflammatory disease.

  本文提供了一种异吲哚啉衍生物、中间体、制备方法、药物组合物及其用途。异吲哚啉衍生物及其药物组合物可以调节免疫细胞因子的产生或活性，从而有效治疗癌症和炎症性疾病。
• IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO
  申请人：Plemper Richard K.

  公开号：US20140080828A1

  公开（公告）日：2014-03-20

  This disclosure relates to antiviral compounds disclosed herein and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising 2-((benzo[d]imidazol-2-yl)thio)-N-phenylpropanamide derivatives, N-phenyl-2-((1-phenyl-benzo[d]imidazol-2-yl)thio)propanamide derivatives, or 2-((benzo[d]imidazol-2-yl)thio)-N-(2-chloro-4-methylphenyl)propanamide derivatives. The derivatives may be substituted with one or more substituents. Typically, the pharmaceutical composition comprises a compound of Formula (I), or salt, prodrug, or ester thereof wherein X, Y, and R1 to R7 are described herein.
• ISOINDOLINE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
  申请人：KANGPU BIOPHARMACEUTICALS, LTD.

  公开号：US20170313676A1

  公开（公告）日：2017-11-02

  Provided are an isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof. The isoindoline derivative and the pharmaceutical composition thereof can regulate the production or activity of immunological cytokines, thus effectively treating cancer and inflammatory disease.

表征谱图