2,3,7,8,12,13,17,18-octaethylporphyrin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 2,3,7,8,12,13,17,18-octaethylporphyrin
• 化学式: C₃₆H₄₄N₄
• 分子量: 532.8
• InChiKey: IOHGVYCKSQNOFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  40
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers
  申请人：Lindsey S. Jonathan

  公开号：US20060009638A1

  公开（公告）日：2006-01-12

  Porphyrin compounds having a surface attachment group coupled thereto at the 5 position are described. The surface attachment group has the formula: wherein R is —CHCH 2 or —CCH and Ar is an aromatic group. Methods and intermediates useful for making such compounds are also described.

  描述了在5位点上具有表面附着基团的卟啉化合物。表面附着基团的化学式为：其中R为—CHCH2或—CCH，Ar为芳香基团。还描述了制备这类化合物所用的方法和中间体。
• Pharmaceutical compositions comprising metal complexes
  申请人：——

  公开号：US20020049190A1

  公开（公告）日：2002-04-25

  A compound of the formula [M a (X b L) c Y d Z e ] nt± Formula I wherein: M is a metal ion or a mixture of metal ions; X is a cation or a mixture of cations; L is a ligand, or mixture of ligands each containing at least two different donor atoms selected from the elements of Group IV, Group V or Group VI of the Periodic Table; Y is a ligand or a mixture of the same or different ligands each containing at least one donor atom or more than one donor atom selected from the elements of Group IV, Group V or Group VI of the Periodic Table; and Z is a halide or pseudohalide ion or a mixture of halide ions and pseudohalide ions; and wherein: a=1-3; b=0-12; c=0-18; d=0-18; e=0-18; and n=0-10; provided that at least one of c, d and e is 1 or more; wherein c is 0: b is also 0; wherein a is 1: c, d and e are not greater than 9; and wherein a is 2: c, d and e are not greater than 12.

  该化合物的化学式为[Ma(XbL)cYdZe]nt±Formula I其中：M是金属离子或金属离子的混合物；X是阳离子或阳离子的混合物；L是配体，或者是至少含有周期表IV、V或VI族元素中至少两种不同供体原子的配体混合物；Y是配体或者是至少含有周期表IV、V或VI族元素中至少一个供体原子或多个供体原子的相同或不同配体的混合物；Z是卤素或伪卤素离子或卤素离子和伪卤素离子的混合物；并且其中：a=1-3；b=0-12；c=0-18；d=0-18；e=0-18；n=0-10；前提是c、d和e中至少有一个大于等于1；其中c为0时：b也为0；其中a为1时：c、d和e均不大于9；其中a为2时：c、d和e均不大于12。
• Nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery carriers
  申请人：——

  公开号：US20040076585A1

  公开（公告）日：2004-04-22

  The present invention relates to a method using nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery agents. Pharmaceutical agents can be packed or condensed inside nanoparticles of cyclic tetrapyrrolic compounds and delivered to cells. In vitro experiments showed nanoparticles of cyclic tetrapyrrolic compounds can be effectively delivered into cells.

  本发明涉及一种利用环四吡咯烷化合物的纳米颗粒作为基因和药物传递剂的方法。药物可以被包装或浓缩在环四吡咯烷化合物的纳米颗粒内，并传递到细胞中。体外实验表明，环四吡咯烷化合物的纳米颗粒可以有效地传递到细胞内。
• Method to prepare porphyrin nanoparticles and its application as oxidation catalyst
  申请人：——

  公开号：US20030232982A1

  公开（公告）日：2003-12-18

  The present invention relates to a method to prepare porphyrin nanoparticles and its application as oxidation catalyst. Mixing solvent techniques was used to prepare porphyrin nanoparticles. The sizes of the resulted porphyin nanoparticles are in the range of 1-1000 nm. The resulted porphyrin nanoparticles were characterized by DLS, AFM and UV-Vis. The nanoparticles are stable in air from weeks to months and has been successfully transferred to Al 2 O 3 and silica gel surface. The present invention also related to a method to use nanoparticles of porphyrins as catalyst for epoxidation reactions of olefins and hydroxylation reactions of saturated hydrocarbons. By loading the nanoparticles onto the surface of Al 2 O 3 and silica gel, excellent catalytic activities were obtained in oxidation reactions.

  本发明涉及一种制备卟啉纳米颗粒及其作为氧化催化剂的应用方法。采用混合溶剂技术制备卟啉纳米颗粒，所得到的卟啉纳米颗粒的尺寸在1-1000纳米范围内。所得到的卟啉纳米颗粒通过DLS、AFM和UV-Vis进行表征。这些纳米颗粒在空气中稳定，可以保持数周至数月，并成功地转移到Al2O3和二氧化硅凝胶表面。本发明还涉及一种使用卟啉纳米颗粒作为烯烃环氧化反应和饱和烃羟化反应催化剂的方法。通过将纳米颗粒载入Al2O3和二氧化硅凝胶表面，可以获得优异的氧化反应催化活性。
• [EN] BIS-PHENANTHROLINE IRON MACROCYCLE COMPLEX FOR OXYGEN REDUCTION REACTION<br/>[FR] COMPLEXE MACROCYCLIQUE DE BIS-PHÉNANTHROLINE-FER POUR RÉACTION DE RÉDUCTION D'OXYGÈNE
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2020186264A1

  公开（公告）日：2020-09-17

  Disclosed are compounds, compositions, and methods useful for the oxygen reduction reaction (ORR) and capable of operating efficiently at low overpotentials.

  本发明涉及用于氧还原反应（ORR）的化合物、组合物和方法，能够在低过电位下高效运作。