2,3,5,6-Tetramethyl-4-thiaheptane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2,3,5,6-Tetramethyl-4-thiaheptane
• 英文别名: 2-methyl-3-(3-methylbutan-2-ylsulfanyl)butane
• 化学式: C₁₀H₂₂S
• 分子量: 174.35
• InChiKey: WGOMZHJEFQQPAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Triptolide Derivatives And Their Uses
  申请人：Li Yuanchao

  公开号：US20070197476A1

  公开（公告）日：2007-08-23

  The invention relates to triptolide derivatives of Formula (I), their pharmaceutically acceptable salts and optical isomers, Formula (I): wherein, C5 and C6 connect with each other by a C—C single bond or double bond; when C5 and C6 are connected with C—C single bond, X and Y represents independently hydrogen, oxygen, hydroxyl, halogen, lower alkyl-oxy, lower alkyl-amino, mercapto, lower alkyl-thio, the group of formula —OCOR, —OSO 2 R or —OPO(OH) 2 , each of which is attached to C5 and C6, R represents —(CH 2 )nCO 2 Na, —(CO 2 )nCO 2 K, or —(CH 2 )nCH 3 , wherein n=1-6; Z represents hydrogen, oxygen, hydroxyl, halogen, lower alkyl-oxy, lower alkyl-amino, mercapto, lower alkyl-thio, the group of formula —OCOR, —OSO 2 R or —OPO(OH)2, each of which is linked at C14-position, R represents —(CH2)nCO2Na, —(CO 2 )nCO 2 K, or —(CH 2 )nCH 2 , wherein n=1-6; wherein, the “_” linked with X, Y, and Z represents “ ” or “ ”, but X and Y cannot both be hydrogen atom at the same time, the methods for preparing them and their use as antiphlogistic agent, immunosuppressive agent or therapeutic agent for other related diseases.

  本发明涉及式（I）的三酰甲基衍生物、其药学上可接受的盐和光学异构体，式（I）如下： 其中，C5和C6通过C—C单键或双键连接；当C5和C6通过C—C单键连接时，X和Y分别表示氢、氧、羟基、卤素、较低的烷氧基、较低的烷基氨基、巯基、较低的烷硫基、式—OCOR、—OSO2R或—OPO（OH）2的基团，每个基团都连接在C5和C6上，其中R表示—（CH2）n Na、—（CO2）n K或—（ ）nCH3，其中n为1-6；Z表示氢、氧、羟基、卤素、较低的烷氧基、较低的烷基氨基、巯基、较低的烷硫基、式—OCOR、—OSO2R或—OPO（OH）2的基团，每个基团都连接在C14位点，其中R表示—（ ）n Na、—（ ）n K或—（ ）n ，其中n为1-6；其中，与X、Y和Z连接的“_”表示“”或“”，但X和Y不能同时为氢原子，本发明还涉及其制备方法以及作为抗炎剂、免疫抑制剂或治疗其他相关疾病的治疗剂的用途。
• PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS
  申请人：Sumitomo Seika Chemicals Co. Ltd.

  公开号：EP2441751A1

  公开（公告）日：2012-04-18

  An object of the present invention is to provide a method for preparation of an alkyl sulfone compound simply and safely with high yield, and an alkyl sulfone compound. The present invention is a method for preparing an alkyl sulfone compound represented by formula (2), comprising: oxidizing an alkyl sulfide compound represented by formula (1) using an oxidizing agent in the presence of a tungstate catalyst: in formula (1), R1 represents a C1-C3 alkyl group, and R2 represents a C3-C5 alkyl group, in formula (2), R1 and R2 are the same alkyl groups as R1 and R2 in formula (1), respectively.

  本发明的目的是提供一种简单、安全、高产率地制备烷基砜化合物和烷基砜化合物的方法。 本发明是一种制备由式（2）表示的烷基砜化合物的方法，包括 在钨酸盐催化剂存在下，使用氧化剂氧化式（1）代表的烷基砜化合物： 式（1）中，R1 代表 C1-C3 烷基，R2 代表 C3-C5 烷基、 在式 (2) 中，R1 和 R2 分别是与式 (1) 中的 R1 和 R2 相同的烷基。
• ODORISATION OF FUEL GAS WITH LOW-SULFUR ODORANTS
  申请人：Mansfeld Gerd

  公开号：US20090064585A1

  公开（公告）日：2009-03-12

  The use is described of a mixture containing A) at least two different acrylic acid C 1 -C 6 alkyl esters; B) at least one compound from the group comprising C 1 -C 8 mercaptans, C 4 -C 12 thiophenes, C 2 -C 8 sulfides or C 2 -C 8 disulfides; C) at least one compound from the group comprising norbornenes, C 1 -C 5 carboxylic acids, C 1 -C 8 aldehydes, C 6 -C 14 phenols, C 7 -C 14 anisoles or C 4 -C 14 pyrazines; D) optionally an antioxidant for the odorisation of fuel gas having a methane content of at least 60 wt. %. Corresponding fuel gases and processes for the odorisation of fuel gases are also described.
• US4122258A
  申请人：——

  公开号：US4122258A

  公开（公告）日：1978-10-24
• US7626044B2
  申请人：——

  公开号：US7626044B2

  公开（公告）日：2009-12-01