Phenylacetic acid, 2-methylcyclohex-2-enyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Phenylacetic acid, 2-methylcyclohex-2-enyl ester
• 英文别名: (2-methylcyclohex-2-en-1-yl) 2-phenylacetate
• 化学式: C₁₅H₁₈O₂
• 分子量: 230.3
• InChiKey: PPPMRKYJQZZHGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] METHOD FOR TREATING AN AUTOIMMUNE NEUROLOGICAL DISEASE AND/OR NEURODEGENERATIVE DISEASE AND PHARMACEUTICAL FORMULATIONS FOR A LIQUID DOSAGE FORM AND A CONTROLLED RELEASE DOSAGE FORM<br/>[FR] PROCÉDÉ DE TRAITEMENT D'UNE MALADIE NEUROLOGIQUE AUTO-IMMUNE ET/OU D'UNE MALADIE NEURODÉGÉNÉRATIVE ET FORMULES PHARMACEUTIQUES POUR UNE FORME GALÉNIQUE LIQUIDE ET UNE FORME GALÉNIQUE À LIBÉRATION CONTRÔLÉE
  申请人：IND TECH RES INST

  公开号：WO2019002889A1

  公开（公告）日：2019-01-03

  A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: Formula (I); Formula (II); Formula (III), wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, -(C=O)–alkyl, –(C=O)–aryl, –(C=O)–alkyl-aryl, –(C=O)–heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of -OH, -NO2, -NH2, -NR3R4, carbonyl, alkoxyl, alkyl or -OCF3, wherein R3 and R4 independently are H, alkyl, -SO2CH3, -(C=O)-CH3 or -(C=O)-NH2.