2-(1-Propylbutyl)pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(1-Propylbutyl)pyridine
• 英文别名: 2-heptan-4-ylpyridine
• 化学式: C₁₂H₁₉N
• 分子量: 177.29
• InChiKey: ZQEAUDWGKFSWMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

  公开号：US20150203489A1

  公开（公告）日：2015-07-23

  The present invention relates to compounds of the following general formula (I): wherein: R 1 is notably a group —NR a R b , R a and R b forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R 2 is notably an aryl comprising from 5 to 30 atoms, and R 3 is notably an alkenyl comprising from 1 to 20 carbon atoms.

  本发明涉及以下通式(I)的化合物： 其中： R1特别地是一个基团—NRaRb，Ra和Rb与它们所连接的氮原子一起形成一个包含5至30个原子的杂环； R2特别地是一个包含5至30个原子的芳基； R3特别地是一个包含1至20个碳原子的烯基。
• Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

  公开号：US10202372B2

  公开（公告）日：2019-02-12

  The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.

  本发明涉及以下一般式（I）的化合物：其中：R1 明显是一个基团—NRaRb，Ra 和 Rb 与它们结合的氮原子一起形成一个含有 5 到 30 个原子的杂环，R2 明显是一个含有 5 到 30 个原子的芳基，R3 明显是一个含有 1 到 20 个碳原子的烯基。
• 4-ALKYL SUBSTITUTED PYRIDINES AS ODIFEROUS SUBSTANCES
  申请人：Oertling Heiko

  公开号：US20100130624A1

  公开（公告）日：2010-05-27

  The present invention primarily concerns certain 4-alkyl pyridines of the following formula (I), wherein R is C 8 -C 12 alkyl, odiferous substance mixtures and aromatic substance mixtures containing these 4-alkyl pyridines, the respective uses thereof as an odiferous or aromatic substance (mixture) and corresponding perfumed products.

  本发明主要涉及以下式子(I)的某些4-烷基吡啶，其中R为C8-C12烷基，包含这些4-烷基吡啶的气味物混合物和芳香物混合物，它们分别用作气味或芳香物质(混合物)及相应的香水制品。
• PIPERAZINE-SUBSTITUTED [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP2938344B1

  公开（公告）日：2017-06-21
• O-GLCNAC TRANSFERASE (OGT) INHIBITORS AND USES THEREOF
  申请人：President and Fellows of Harvard College

  公开号：US20170166558A1

  公开（公告）日：2017-06-15

  The present invention provides inhibitors of O-GlcNAc transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, metabolic diseases, neurodegenerative diseases, proliferative diseases (e.g., cancers), autoimmune diseases, and inflammatory diseases.