4-Ethylbenzoic acid, 2,2-dimethylpropyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Ethylbenzoic acid, 2,2-dimethylpropyl ester
• 英文别名: 2,2-dimethylpropyl 4-ethylbenzoate
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.31
• InChiKey: QQERUDMQWULXOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Method of radio-sensitizing tumors using a radio-sensitizing agent
  申请人：Diebold James L.

  公开号：US20080146556A1

  公开（公告）日：2008-06-19

  The present invention relates to a method of treating cancer using PARP inhibitors as radio-sensitization agents of tumors. Specifically the present invention relates to a method of radio-sensitization of tumors using a compound of Formula (I) or a pharmaceutically acceptable salt form thereof. The present invention also relates to a pharmaceutical compositions of PARP inhibitors for radiosensitizing tumors.