Phenol, 2,4-bis(1-methylethyl)-, acetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: Phenol, 2,4-bis(1-methylethyl)-, acetate
• 英文别名: [2,4-di(propan-2-yl)phenyl] acetate
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.31
• InChiKey: PYXQUTGAJSHHRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS<br/>[FR] INHIBITEURS HSP90 À BASE DE COUMARINE À SUBSTITUANTS D'URÉE ET D'ÉTHER
  申请人：UNIV KANSAS

  公开号：WO2015070238A2

  公开（公告）日：2015-05-14

  Compounds of the formulas: wherein: R1-R4, X1, Y1, and A are as defined herein are provided. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds are are useful for the treatment of a disease or disorder. In some embodiments, the disease or disorder is a proliferative disease such as cancer.