2-[4-[(4-Phenylphenyl)methyl]piperazin-1-yl]ethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[4-[(4-Phenylphenyl)methyl]piperazin-1-yl]ethanol
• 化学式: C₁₉H₂₄N₂O
• 分子量: 296.4
• InChiKey: QHCVXTIIAKGDPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  26.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOUNDS FOR TREATING MYELIN RELATED DISORDERS
  申请人：Case Western Reserve University

  公开号：US20210353642A1

  公开（公告）日：2021-11-18

  Disclosed is a pharmaceutical composition comprising a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent. Also disclosed is a method of treating a myelin related disorder in a subject, the method comprising administering to the subject an effective amount of a compound of Structural Formula (I) or a pharmaceutical composition comprising the compound of Structural Formula (I). The variables of Structural Formula (I) are described herein.