N-(3-chloro-4-methylphenyl)-4-ethoxybenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3-chloro-4-methylphenyl)-4-ethoxybenzamide
• 化学式: C₁₆H₁₆ClNO₂
• 分子量: 289.75
• InChiKey: SXLATJIAJJMHNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• MODULATING IRES-MEDIATED TRANSLATION
  申请人：Thompson Sunnie R.

  公开号：US20120065247A1

  公开（公告）日：2012-03-15

  Provided herein are compounds and methods for use in preventing or treating a viral infection mediated by a virus comprising an IRES-containing RNA molecule or cancer related to an increase or decrease in IRES-mediated translation of an RNA molecule. Also provided are methods of inhibiting or promoting IRES-mediated translation. Also provided are methods of screening for an agent that inhibits IRES-mediated translation.