2,3-Dichloro-4-ethoxypyridine | 887571-10-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,3-Dichloro-4-ethoxypyridine
• CAS: 887571-10-0
• 化学式: C₇H₇Cl₂NO
• mdl: MFCD00234298
• 分子量: 192.04
• InChiKey: XUMOFJMZJPYACB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] BTK INHIBITORS<br/>[FR] INHIBITEURS DE BTK
  申请人：MERCK SHARP & DOHME

  公开号：WO2016106625A1

  公开（公告）日：2016-07-07

  Provided are Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and their use in therapy. In particular, the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders is provided.
• [EN] HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS<br/>[FR] INHIBITEURS HÉTÉROCYCLIQUES DE WDR5 UTILISÉS EN TANT QUE COMPOSÉS ANTICANCÉREUX
  申请人：NOVARTIS AG

  公开号：WO2021026672A1

  公开（公告）日：2021-02-18

  Provided are compounds of Formula (I) and pharmaceutical acceptable salts thereof, which are inhibitors of WDR5. Also providing pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compounds.