N-[(1S)-1-phenylpropyl]cyclobutanecarboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(1S)-1-phenylpropyl]cyclobutanecarboxamide
• 化学式: C₁₄H₁₉NO
• mdl: MFCD03758197
• 分子量: 217.31
• InChiKey: KEEDDACEYQLHIH-ZDUSSCGKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] CELL ENTRY-MODULATING AGENTS AND USES THEREFOR<br/>[FR] AGENTS MODULATEURS DE L'ENTRÉE CELLULAIRE ET LEURS UTILISATIONS
  申请人：UNIV GRIFFITH

  公开号：WO2021222988A1

  公开（公告）日：2021-11-11

  The present disclosure relates to peptides comprising an amino acid sequence set forth in SEQ ID NO: 1 or 2. Methods of using these peptides to treat or prevent an infection caused by an angiotensin-converting enzyme 2 (ACE2)-interacting coronavirus, elicit an immune response to an ACE2-interacting coronavirus, detect an infection by an ACE2-interacting coronavirus, or identify agents which inhibit the interaction of an ACE2-interacting coronavirus with the ACE2 receptor, are further disclosed. Furthermore, this disclosure pertains to methods of treating a coronavirus infection comprising the administration of an ACE2- interacting compound, and novel compounds for this purpose.