N-(2,4,6-trimethylphenyl)ethanesulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,4,6-trimethylphenyl)ethanesulfonamide
• 化学式: C₁₁H₁₇NO₂S
• mdl: MFCD03387986
• 分子量: 227.33
• InChiKey: KOHKEPYKYCRXHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Polyamine compounds and compositions for use in conjection with cancer therapy
  申请人：Fahl L Kathleen

  公开号：US20050027016A1

  公开（公告）日：2005-02-03

  The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more chemoprotective polyamines formulated for topical or local delivery to epithelial or mucosal cells are disclosed. Methods of administering the pharmaceutical preparations are also disclosed.

  本发明提供了新型多胺化合物和药物组合物，可配合癌症化疗或放疗使用。这些化合物局部给药，可防止化疗或放疗的不良副作用，如脱发、粘膜炎和皮炎。本发明公开了包含一种或多种化学保护性多胺的药物制剂，用于局部或局部给药上皮细胞或粘膜细胞。此外，还公开了给药方法。
• POLYAMINE COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY
  申请人：WISCONSIN ALUMNI RESEARCH FOUNDATION

  公开号：EP1478618A1

  公开（公告）日：2004-11-24
• Polyamine compounds and compositions for use in conjunction with cancer therapy
  申请人：——

  公开号：US20030185778A1

  公开（公告）日：2003-10-02

  The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more chemoprotective polyamines formulated for topical or local delivery to epithelial or mucosal cells are disclosed. Methods of administering the pharmaceutical preparations are also disclosed.
• Amino thiol compounds and compositions for use in conjunction with cancer therapy
  申请人：Fahl E. William

  公开号：US20050101676A1

  公开（公告）日：2005-05-12

  The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more chemoprotective polyamines or amino thiols formulated for topical or local delivery to epithelial or mucosal cells are disclosed. Methods of administering the pharmaceutical preparations are also disclosed.
• US7314959B2
  申请人：——

  公开号：US7314959B2

  公开（公告）日：2008-01-01