N-[4-(propan-2-yl)phenyl]butanamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[4-(propan-2-yl)phenyl]butanamide
• 英文别名: N-(4-propan-2-ylphenyl)butanamide
• 化学式: C₁₃H₁₉NO
• mdl: MFCD00751530
• 分子量: 205.3
• InChiKey: IDDDOJJSNZTWIQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.461
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE
  申请人：SHY Therapeutics LLC

  公开号：US20170174699A1

  公开（公告）日：2017-06-22

  Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are useful in compositions and methods for treating cancer and inflammatory disease.

  本文提供了抑制MAPK磷酸化的化合物，因此可用于治疗癌症和炎症性疾病的组合物和方法。
• Multimeric mannosides, a process for preparing the same and their uses as a drug
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

  公开号：US10273313B2

  公开（公告）日：2019-04-30

  The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia coli infections. Exemplary compounds are:

  本发明涉及多聚甘露糖苷、多聚甘露糖苷的制备方法及其在治疗大肠杆菌感染中的医药用途。示例化合物有
• TXNIP-TRX complex inhibitors and methods of using the same
  申请人：CITY OF HOPE

  公开号：US11324731B2

  公开（公告）日：2022-05-10

  Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex.

  本文特别公开了抑制硫氧还蛋白-硫氧还蛋白-相互作用蛋白（TXNIP-TRX）复合物的化合物和方法。
• TXNIP-TRX COMPLEX INHIBITORS AND METHODS OF USING THE SAME
  申请人：CITY OF HOPE

  公开号：US20200085800A1

  公开（公告）日：2020-03-19

  Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex.
• [EN] COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE<br/>[FR] COMPOSÉS POUR LE TRAITEMENT DU CANCER ET DE MALADIES INFLAMMATOIRES
  申请人：SHY THERAPEUTICS LLC

  公开号：WO2017112777A1

  公开（公告）日：2017-06-29

  Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are compositions and methods for treating cancer and inflammatory disease.