N-(1,3-benzodioxol-5-ylmethyl)-4-(propan-2-yloxy)benzamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: N-(1,3-benzodioxol-5-ylmethyl)-4-(propan-2-yloxy)benzamide
• 英文别名: N-(1,3-benzodioxol-5-ylmethyl)-4-propan-2-yloxybenzamide
• 化学式: C₁₈H₁₉NO₄
• 分子量: 313.3
• InChiKey: BBPBYFPGYPINGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  56.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• NEURODEGENERATIVE DISEASE THERAPEUTIC AGENT
  申请人：Ariga Hiroyoshi

  公开号：US20130109714A1

  公开（公告）日：2013-05-02

  Provided is an unprecedented composition that is not a conventional symptomatic treatment, but makes possible the fundamental treatment of current neurodegenerative diseases by inhibiting oxidative-stress induced nerve-cell death. The disclosed neurodegenerative disease therapeutic agent includes a compound, or a salt of said compound, that inhibits oxidative-stress induced nerve-cell death to a high degree and is an agent used in the treatment of neurodegenerative diseases such as Parkinson's disease.