3-methyl-N-phenethylbenzenesulfonamide | 670271-70-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methyl-N-phenethylbenzenesulfonamide
• 英文别名: 3-methyl-N-(2-phenylethyl)benzenesulfonamide
• CAS: 670271-70-2
• 化学式: C₁₅H₁₇NO₂S
• 分子量: 275.4
• InChiKey: LIORBEFOYWXZGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY
  申请人：THE GENERAL HOSPITAL CORPORATION

  公开号：US20160271276A1

  公开（公告）日：2016-09-22

  Disclosed herein are histone deacetylase imaging agents for positron emission tomography and related imaging methods using the histone deacetylase imaging agents. The histone deacetylase imaging agents may be a compound of formula (I): wherein R 1 is a moiety including a positron emitter; R 2 represents hydrogen, or substituted or unsubstituted alkyl, or substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and n is an integer selected from 0 or 1. In one version of the compound of formula (I), R 1 is a moiety including an adamantyl group.