(1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) pyridine-4-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) pyridine-4-carboxylate
• 化学式: C₁₅H₂₂N₂O₃
• 分子量: 278.35
• InChiKey: GLGSGNBIQQKLDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  62.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• MODULATORS OF OCULAR OXIDATIVE STRESS
  申请人：MATA Nathan L.

  公开号：US20090253745A1

  公开（公告）日：2009-10-08

  Described herein are compounds, compositions and methods directed to the treatment of ophthalmic conditions characterized by oxidative stress or damage in a subject by reducing the reactive oxygen species in the subject. Also described herein are methods for reducing ophthalmic photooxidative damage in a subject.

  本文描述了化合物、组合物和方法，用于通过减少受试者中的反应性氧化物种来治疗以氧化应激或损伤为特征的眼部疾病。本文还描述了减少受试者眼部光氧化损伤的方法。
• [EN] MODULATORS OF OCULAR OXIDATIVE STRESS<br/>[FR] MODULATEURS DE STRESS OXYDATIF OCULAIRE
  申请人：SIRION THERAPEUTICS INC

  公开号：WO2009070693A2

  公开（公告）日：2009-06-04

  Described herein are compounds, compositions and methods directed to the treatment of ophthalmic conditions characterized by oxidative stress or damage in a subject by reducing the reactive oxygen species in the subject. Also described herein are methods for reducing ophthalmic photooxidative damage in a subject.