2-chloro-N-[2-(dimethylamino)ethyl]benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloro-N-[2-(dimethylamino)ethyl]benzamide
• 化学式: C₁₁H₁₅ClN₂O
• 分子量: 226.7
• InChiKey: BYAQVQHPZHTOAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Carbapenem compounds and compositions for the treatment of bacterial infections
  申请人：FOB Synthesis, Inc.

  公开号：US10933051B2

  公开（公告）日：2021-03-02

  The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

  本发明提供了用于治疗细菌感染（包括耐药性或多重耐药性细菌感染）的碳青霉烯类化合物和药物组合物，以及使用此类化合物和/或组合物治疗此类感染的方法。本发明包括向需要治疗的宿主施用有效量的碳青霉烯类化合物或其盐和/或原药。
• Carbapenem Compounds and Compositions for the Treatment of Bacterial Infections
  申请人：FOB Synthesis, Inc.

  公开号：US20200155508A1

  公开（公告）日：2020-05-21

  The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.