N-(4-phenoxyphenyl)propanamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-phenoxyphenyl)propanamide
• 化学式: C₁₅H₁₅NO₂
• mdl: MFCD01354292
• 分子量: 241.28
• InChiKey: IYSAOZFRXQYCDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.133
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS<br/>[FR] ANTAGONISTES DES RÉCEPTEURS DE SPHINGOSINE-1-PHOSPHATE
  申请人：EXELIXIS INC

  公开号：WO2010045580A1

  公开（公告）日：2010-04-22

  This disclosure relates to sphingosine-1 -phosphate (SlP) receptor antagonists, compositions comprising the SlP receptor antagonists and methods for using and processes for making the SlP receptor antagonists. In particularly, this disclosure relates to sphingosine-1 -phosphate 1 (SlPl) receptor antagonists, compositions comprising the SlPl receptor antagonist and methods for using the SlPl receptor antagonist, such as in the treatment of cancer, and processes for making the SlPl receptor antagonists.

  这项披露涉及神经酰胺-1-磷酸(S1P)受体拮抗剂，包括该S1P受体拮抗剂的组合物以及使用和制备该S1P受体拮抗剂的方法。特别是，这项披露涉及神经酰胺-1-磷酸1(S1P1)受体拮抗剂，包括该S1P1受体拮抗剂的组合物以及使用该S1P1受体拮抗剂的方法，例如在癌症治疗中，并且包括制备该S1P1受体拮抗剂的方法。
• Modified graphene, method of producing modified graphene, modified graphene-resin composite, modified graphene sheet, and modified graphene dispersion
  申请人：CANON KABUSHIKI KAISHA

  公开号：US11518889B2

  公开（公告）日：2022-12-06

  The modified graphene includes a structure represented by the following formula (I), wherein the modified graphene has a ratio (g/d) of an intensity “g” of a G band to an intensity “d” of a D band of 1.0 or more in a Raman spectroscopy spectrum thereof: Gr1-Ar1-X1-(Y1) n1 (I) in the formula (I), Gr1 represents a single-layer graphene or a multilayer graphene, Ar1 represents an arylene group having 6 to 18 carbon atoms, X1 represents a single bond, a linear, branched, or cyclic alkylene group having 1 to 20 carbon atoms, or a group obtained by substituting at least one carbon atom in a linear, branched, or cyclic alkylene group having 1 to 20 carbon atoms with at least one structure selected from the group consisting of —O—, —NH—, —CO—, —COO—, —CONH—, and an arylene group.

  改性石墨烯包括下式(I)所代表的结构，其中改性石墨烯在其拉曼光谱中的G波段强度 "g "与D波段强度 "d "之比(g/d)为1.0或以上： Gr1-Ar1-X1-(Y1) n1 (I) 在式 (I) 中，Gr1 代表单层石墨烯或多层石墨烯，Ar1 代表具有 6 至 18 个碳原子的芳烯基团，X1 代表单键、具有 1 至 20 个碳原子的直链、支链或环状亚烷基，或将具有 1 至 20 个碳原子的直链、支链或环状亚烷基中的至少一个碳原子用至少一种选自 -O-、-NH-、 -O-、-NH-、-CO-、-COO-、-CONH- 和芳烯基所组成的组中的至少一种结构。
• CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE
  申请人：Abbott Laboratories

  公开号：EP0677039A1

  公开（公告）日：1995-10-18
• SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS
  申请人：Exelixis, Inc.

  公开号：EP2346821A1

  公开（公告）日：2011-07-27
• SYNERGISTIC COMBINATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS AND ANTIMICROTUBULE AGENTS
  申请人：Exelixis, Inc.

  公开号：EP2349252A2

  公开（公告）日：2011-08-03