N-[diphenyl(2-phenylethynyl)-lambda5-phosphanylidene]-4-methylbenzamide | 954412-94-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[diphenyl(2-phenylethynyl)-lambda5-phosphanylidene]-4-methylbenzamide
• 英文别名: N-[diphenyl(2-phenylethynyl)-λ5-phosphanylidene]-4-methylbenzamide
• CAS: 954412-94-3
• 化学式: C₂₈H₂₂NOP
• 分子量: 419.463
• InChiKey: KEBCJJXASHYPAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-[diphenyl(2-phenylethynyl)-lambda5-phosphanylidene]-4-methylbenzamide 、 以 苯 为溶剂， 反应 4.0h， 以72%的产率得到4-methyl-N-[[(E)-2-[(4-methylphenyl)imino-diphenyl-lambda5-phosphanyl]-2-phenylethenyl]-diphenyl-lambda5-phosphanylidene]benzamide
  参考文献：
  名称：

  Regio- and stereoselective nucleophilic additions of amines, thiols and aminophosphanes to the CC bond of P,P-diphenyl-P-(2-phenylethynyl)-λ5-phosphazenes

  摘要：

  Nitrogen and sulfur nucleophiles, such as amines, thiophenols, and aminophosphanes, add to the triple bond of P-ethynyl-lambda(5)-phosphazenes to give regio and diastereoselectively P-ethenyl-lambda(5)-phosphazenes. An equally selective substitution reaction, occurring by an addition-elimination pathway, on bis(iminophosphoranyl)ethenes has been also achieved. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.07.148
• 作为产物：
  描述：

  苯基乙炔基二苯基膦 、 4-甲基苯甲酰叠氮化物 以 二氯甲烷 为溶剂， 以94%的产率得到N-[diphenyl(2-phenylethynyl)-lambda5-phosphanylidene]-4-methylbenzamide
  参考文献：
  名称：

  Regio- and stereoselective nucleophilic additions of amines, thiols and aminophosphanes to the CC bond of P,P-diphenyl-P-(2-phenylethynyl)-λ5-phosphazenes

  摘要：

  Nitrogen and sulfur nucleophiles, such as amines, thiophenols, and aminophosphanes, add to the triple bond of P-ethynyl-lambda(5)-phosphazenes to give regio and diastereoselectively P-ethenyl-lambda(5)-phosphazenes. An equally selective substitution reaction, occurring by an addition-elimination pathway, on bis(iminophosphoranyl)ethenes has been also achieved. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.07.148

文献信息

• Regio- and stereoselective nucleophilic additions of amines, thiols and aminophosphanes to the CC bond of P,P-diphenyl-P-(2-phenylethynyl)-λ5-phosphazenes
  作者：Mateo Alajarín、Carmen López-Leonardo、Pilar Llamas-Lorente、Rosalía Raja

  DOI：10.1016/j.tetlet.2007.07.148

  日期：2007.9

  Nitrogen and sulfur nucleophiles, such as amines, thiophenols, and aminophosphanes, add to the triple bond of P-ethynyl-lambda(5)-phosphazenes to give regio and diastereoselectively P-ethenyl-lambda(5)-phosphazenes. An equally selective substitution reaction, occurring by an addition-elimination pathway, on bis(iminophosphoranyl)ethenes has been also achieved. (c) 2007 Elsevier Ltd. All rights reserved.