(3,5-Dimethylphenyl)-(4-methylpiperazin-1-yl)methanone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3,5-Dimethylphenyl)-(4-methylpiperazin-1-yl)methanone
• 化学式: C₁₄H₂₀N₂O
• mdl: MFCD06010446
• 分子量: 232.32
• InChiKey: COWFNBFSVSSGLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• N-SULFONYLCARBOXIMIDAMIDE APOPTOSIS PROMOTERS
  申请人：Elmore Steven W.

  公开号：US20100035879A1

  公开（公告）日：2010-02-11

  Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

  具有公式的化合物是凋亡促进剂。还公开了制备这些化合物的方法、含有这些化合物的组合物以及使用这些化合物的治疗方法。
• Glycopeptide Antibiotic Monomer Derivatives
  申请人：Arimoto Hirokazu

  公开号：US20080097078A1

  公开（公告）日：2008-04-24

  Novel glycopeptide antibiotic derivatives. These derivatives are represented by the formula (aglycon part of glycopeptide antibiotic derivative)-(Sac-NH)—R A [wherein (aglycon part of glycopeptide antibiotic derivative) is the part formed by removing the sugar part from a known glycopeptide antibiotic derivative; (Sac-NH) part is an amino sugar part or a sugar chain part containing an amino sugar; and R A represents, e.g., the formula —X 1 —Ar 1 —X 2 —Y—X 3 —Ar 2 (wherein X 1 , X 2 , and X 3 each represents 1) a single bond or 2) a heteroatom or heteroatom-containing group selected from the group consisting of —N═, ═N—, —NR 1 —, —O—, etc.; Y represents —NR 2 CO— or —CONR 2 — (wherein R 2 represents hydrogen or lower alkyl), etc.)]. These derivatives have antibacterial activity against vancomycin-resistant bacteria.
• US7358251B2
  申请人：——

  公开号：US7358251B2

  公开（公告）日：2008-04-15
• US7449485B2
  申请人：——

  公开号：US7449485B2

  公开（公告）日：2008-11-11
• US8778874B2
  申请人：——

  公开号：US8778874B2

  公开（公告）日：2014-07-15