N,N'-p-phenylenebis(methacrylamide) | 17695-45-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-p-phenylenebis(methacrylamide)
• 英文别名: 1,4-Bis-methacryloylamino-benzol；N,N'-p-Phenylen-bis-methacrylamid；N,N'-dimethacryloyl 1,4-diaminobenzene；2-Propenamide, N,N'-1,4-phenylenebis[2-methyl-；2-methyl-N-[4-(2-methylprop-2-enoylamino)phenyl]prop-2-enamide
• CAS: 17695-45-3
• 化学式: C₁₄H₁₆N₂O₂
• 分子量: 244.293
• InChiKey: IIHPLWVENBSCEL-UHFFFAOYSA-N

物化性质

• 熔点：
  242-244 °C
• 沸点：
  489.5±41.0 °C(Predicted)
• 密度：
  1.155±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  对苯二胺 、 甲基丙烯酰氯 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 生成 N,N'-p-phenylenebis(methacrylamide)
  参考文献：
  名称：

  The synthesis and characterisation of reactive poly(p-phenylene terephthalamide)s: A route towards compression stable aramid fibres

  摘要：

  Herein we report on the synthesis of reactive poly(p-phenylene terephthalamide) (PPTA) oligomers and the preparation and characterisation of aramid fibres thereof. Methacrylate and maleimide reactive end-groups were found to be sufficiently stable in H2SO4 at 85 degrees C and they were used to prepare reactive PPTA oligomers. Lyotropic spin-dopes could be prepared with up to 20 wt% of reactive oligomer (M-n = 3900 g mol(-1)) and this modification did not interfere with the fibre spinning process and had no effect on the fibre tensile properties. The as-spun fibres did indeed show a modest (+0.1 GPa) improvement in compression strength. A high temperature treatment at 380 degrees C resulted in fibres which all show a significant increase in compressive strength over their as-spun precursors, i.e. from 0.7 to 0.9 GPa. When fibres were treated at 430 degrees C the compression values of the oligomer-modified fibres dropped somewhat, whereas unmodified PPTA displayed a compressive strength of 1.1 GPa. Other favourable fibre properties such as modulus and tenacity were not compromised. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2010.03.015

文献信息

• Photopolymerizable composition
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP1235107A1

  公开（公告）日：2002-08-28

  A photopolymerizable composition that is cured with visible light or an infrared laser and is used as a recording layer in a negative planographic printing plate precursor. The photopolymerizable composition is cured by exposure and includes (A) a polymerizable compound that is solid at 25°C and has at least one radical-polymerizable ethylenically unsaturated double bond in a molecule, (B) a radical polymerization initiator, (C) a binder polymer and, as required, (D) a compound generating heat by infrared exposure.

  一种用可见光或红外激光固化的可光聚合组合物，可用作底片平版印刷板原版中的记录层。这种可光聚合组合物通过曝光固化，包括（A）在 25°C 时为固态的可聚合化合物，其分子中至少有一个可自由基聚合的乙烯不饱和双键；（B）自由基聚合引发剂；（C）粘合剂聚合物；以及根据需要（D）通过红外线曝光产生热量的化合物。
• PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY
  申请人：Centre National de la Recherche Scientifique (C.N.R.S.)

  公开号：EP3112021A1

  公开（公告）日：2017-01-04

  The present invention relates to a method using two-photon stereolithography for preparing molecularly imprinted polymers, notably 3D-structured molecularly imprinted polymers.

  本发明涉及一种利用双光子立体光刻技术制备分子印迹聚合物，特别是三维结构分子印迹聚合物的方法。
• Molecularly imprinted polymers for the treatment and diagnosis of medical conditions
  申请人：——

  公开号：US20020015690A1

  公开（公告）日：2002-02-07

  Improved molecularly imprinted polymers (MIPs) with both higher and more specific binding capacity for particular bile acids and/or salts, including the synthesis of such MIPs, the compounds themselves, and specific applications thereof. As an example of a particularly preferred specific application of these compounds, the present invention encompasses the use of the MIPs as sequestrants in the gastrointestinal tract, particularly in order to bind and therefore remove toxins from the gastrointestinal tract. In addition, the present invention is also useful for treatment of various diseases which are related to, and/or characterized by, an effect of bile acids and salts, such as atherosclerosis, liver disease and various diseases of the gastrointestinal tract. The MIP compounds of the present invention are also useful for combination therapy with other medications and for diagnosis and monitoring of diseases.

  对特定胆汁酸和/或盐具有更高、更特异性结合能力的改进型分子印迹聚合物（MIPs），包括此类 MIPs 的合成、化合物本身及其具体应用。作为这些化合物特别优选的具体应用的一个例子，本发明包括将 MIPs 用作胃肠道中的螯合剂，特别是为了结合并因此清除胃肠道中的毒素。此外，本发明还可用于治疗与胆汁酸和胆汁盐的影响有关和/或以其影响为特征的各种疾病，如动脉粥样硬化、肝病和各种胃肠道疾病。本发明的 MIP 化合物还可用于与其他药物的联合治疗以及疾病的诊断和监测。
• Bentov; Reichmann, Journal of the American Chemical Society, 1952, vol. 74, p. 845
  作者：Bentov、Reichmann

  DOI：——

  日期：——
• MOLECULARLY IMPRINTED POLYMERS AND THEIR USE AS ANTIDANDRUFF AGENTS
  申请人：L'Oréal

  公开号：EP2938641B1

  公开（公告）日：2016-08-24