Cambridge id 5181411

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cambridge id 5181411
• 英文别名: 3-[[4-[(3-carboxyphenyl)carbamoyl]benzoyl]amino]benzoic acid
• 化学式: C₂₂H₁₆N₂O₆
• 分子量: 404.4
• InChiKey: IVVHCUMBWWVAOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  133
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY
  申请人：Wilks Angela

  公开号：US20100081661A1

  公开（公告）日：2010-04-01

  Inhibitors of microbial heme oxygenase and their use for treatment of microbial infections and bioremediation. The inhibitors of microbial heme oxygenase are useful against a new class of antimicrobial agents to target infections that are persistently difficult to combat with the current spectrum of antimicrobial agents. Screening methods for selecting inhibitors of microbial heme oxygenase.
• AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE
  申请人：Garcia Gabriel

  公开号：US20100204219A1

  公开（公告）日：2010-08-12

  The invention relates to novel compounds of formula (I) wherein X, Y, Z represent independently from one another C or N, n stands for 1, 2, 3, m is 0 or 1, p stands for 0 or an integer from 1 to 6, R 1 , R 2 represent independently from one another hydrogen, a halogen atom, a hydroxyl group, a C 1 -C 3 alkyl group and a C 1 -C 3 alkoxy group, R 3 represents, independently from one another if p is not 0, hydrogen, halogen, a C 1 -C 5 linear or branched alkyl, a carboxylyl, a carbomethoxyl, carboethoxyl, a benzyl, an acyl, a hydroxyl, a C 1 -C 4 linear or branched alkoxyl, a trifluoromethyl, a cyano, a morpholino, a 1,3-dioxolyl, an N-acetylamidyl or an amidoyl group, a saturated 5-8 membered ring, a heterocyclic ring, optionally substituted by a C 1 -C 3 alkyl, a hydroxyl or a benzyl group, a C 1 -C 6 alkylsulfonyl, a mono or disubstituted C 1 -C 5 alkyl group, a branched or a cyclic amine, R 6 is H or part of a alicyclic, heteroalicyclic ring system, if m is 0 then C represents CF 3 or a branched or unbranched C 1 -C 4 alkyl group, if m=1 then C represents —CH 2 —O—, —CH 2 —, —CH 2 CH 2 —, —CH 2 CH 2 CH 2 —, —CH 2 (CH 2 )CH 2 — or denotes a chemical bond between N—C or C—C, the CONR 6 group may be linked to C either via its carbon or via its nitrogen atom, CYC stands for a by R 3 substituted or unsubstituted phenyl, pyridinyl, naphthyl, quinolinyl, isoquinolinyl, isoxaxolinyl, thiophenyl, 1,3,4 -thiadiazazolidinyl, furanyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl, morpholinyl, furanyl, cyclohexenyl, and chromen-2-on-yl and its use as a medicament for the treatment of cancer.
• US5286838A
  申请人：——

  公开号：US5286838A

  公开（公告）日：1994-02-15
• [EN] THERMOTROPIC LIQUID CRYSTALLINE POLYAMIDE<br/>[FR] POLYAMIDE LIQUIDE CRISTALLIN THERMOTROPE
  申请人：AKZO NOBEL INC.

  公开号：WO1994011417A1

  公开（公告）日：1994-05-26

  (EN) Thermotropic liquid crystalline copolyamides comprise: (a) a thermoplastic, aliphatic polyamide, such as nylon-6,6; and (b) a mesogen comprising an amide-linked aromatic group segment which is not completely para-linked (namely, is substantially ortho- or meta-linked or a mixture of ortho- and meta-linked) by an amide linkage to an alkylene amide group contained in the mesogen.(FR) Des copolyamides liquides cristallins thermotropes comprennent: (a) un polyamide aliphatique thermoplastique, tel que le nylon-6,6; et (b) un mésogène comprenant un segment de groupe aromatique lié à un amide qui ne présente pas une liaison complète en position para, (ou qui présente sensiblement une liaison en position ortho ou méta ou un mélange d'une liaison en position ortho ou méta), établie par une liaison amide à un groupe amide d'alkylène contenu dans le mésogène.
• [EN] AIRBAG CONTAINING LIQUID CRYSTALLINE POLYMER BLEND<br/>[FR] COUSSIN GONFLABLE DE SECURITE CONTENANT UN MELANGE POLYMERE CRISTALLIN LIQUIDE
  申请人：AKZO NOBEL N.V.

  公开号：WO1995017321A1

  公开（公告）日：1995-06-29

  (EN) The polyamide yarn used in airbag fabric manufacture can be more easily melt processed by adding to the polyamide base polymer a small amount of a thermotropic liquid crystalline copolyamide additive which comprises: (a) a thermoplastic, aliphatic polyamide, such as nylon- 6,6; and (b) a mesogen comprising an amide-linked aromatic group segment which is not completely para-linked (namely, is substantially ortho- or meta-linked or is linked by a mixture of ortho- and meta-linked structures) by an amide linkage to an alkylene amide group contained in the mesogen.(FR) Le fil de polyamide utilisé dans la production de tissu pour coussin gonflable de sécurité peut être plus facilement traité à chaud par addition au polymère de base de polyamide d'une faible quantité d'un additif de copolyamide cristallin liquide thermotropique, lequel comprend: (a) un polyamide thermoplastique aliphatique tel que du nylon 6,6, (b) un mésogen comprenant un segment de groupe aromatique à liaison amyde, lequel ne présente pas de liaison para complète (c'est-à-dire qu'il présente une liaison ortho ou méta ou qu'il est lié par un mélange de structures à liaison ortho et méta) par une liaison amide à un groupe amide d'alkylène contenu dans le mésogen.