Benzoic acid (3,6,8-trimethyl-5,7-dioxo-5,6,7,8-tetrahydro-1H-1,2,6,8,9-pentaazacyclopenta[b]naphthalen-4-yl) ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzoic acid (3,6,8-trimethyl-5,7-dioxo-5,6,7,8-tetrahydro-1H-1,2,6,8,9-pentaazacyclopenta[b]naphthalen-4-yl) ester
• 英文别名: (6,11,13-trimethyl-10,12-dioxo-2,4,5,11,13-pentazatricyclo[7.4.0.03,7]trideca-1,3,6,8-tetraen-8-yl) benzoate
• 化学式: C₁₈H₁₅N₅O₄
• 分子量: 365.3
• InChiKey: RYBWDGAALCAZQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  109
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Method For Altering The Lifespan Of Eukaryotic Organisms
  申请人：Goldfarb David Scott

  公开号：US20090163545A1

  公开（公告）日：2009-06-25

  A method for altering the lifespan of a eukaryotic organism. The method comprises the steps of providing a lifespan altering compound, and administering an effective amount of the compound to a eukaryotic organism, such that the lifespan of the organism is altered. In one embodiment, the compound is identified using the DeaD assay.
• US8642660B2
  申请人：——

  公开号：US8642660B2

  公开（公告）日：2014-02-04
• [EN] METHOD FOR ALTERING THE LIFESPAN OF EUKARYOTIC ORGANISMS<br/>[FR] PROCÉDÉ PERMETTANT DE MODIFIER LA DURÉE DE VIE D'ORGANISMES EUCARYOTES
  申请人：UNIV ROCHESTER

  公开号：WO2009086303A2

  公开（公告）日：2009-07-09

  A method for altering the lifespan of a eukaryotic organism. The method comprises the steps of providing a lifespan altering compound, and administering an effective amount of the compound to a eukaryotic organism, such that the lifespan of the organism is altered. In one embodiment, the compound is identified using the DeaD assay.