(5E)-5-[(3-fluorophenyl)methylidene]-1,3-thiazolidine-2,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: (5E)-5-[(3-fluorophenyl)methylidene]-1,3-thiazolidine-2,4-dione
• 化学式: C₁₀H₆FNO₂S
• 分子量: 223.23
• InChiKey: FHRKKLBIQCOIMF-VMPITWQZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER
  申请人：Musc Foundation for Research Development

  公开号：EP2217235A2

  公开（公告）日：2010-08-18
• Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer
  申请人：Smith Charles D.

  公开号：US20110263664A1

  公开（公告）日：2011-10-27

  The disclosure relates to inhibitors of Pim-1 and/or Pim-2 protein kinase, to compositions comprising one or more inhibitors of Pim-1 and/or Pim-2 protein kinase, and to methods for treating cancer.
• [EN] INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER<br/>[FR] INHIBITEURS DE PROTÉINES KINASES PIM, COMPOSITIONS ET PROCÉDÉS POUR TRAITER LE CANCER
  申请人：MUSC FOUND FOR RES DEV

  公开号：WO2009064486A2

  公开（公告）日：2009-05-22

  The disclosure relates to inhibitors of Pim-1 and/or Pim-2 protein kinase, to compositions comprising one or more inhibitors of Pim-1 and/or Pim-2 protein kinase, and to methods for treating cancer.