3,5-Dioxabicyclo[5.1.0]octane, 8,8-dibromo-4-(1-methylethyl)- | 651036-19-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧环庚烷
• 英文名称: 3,5-Dioxabicyclo[5.1.0]octane, 8,8-dibromo-4-(1-methylethyl)-
• 英文别名: 8,8-dibromo-4-propan-2-yl-3,5-dioxabicyclo[5.1.0]octane
• CAS: 651036-19-0
• 化学式: C₉H₁₄Br₂O₂
• 分子量: 314.017
• InChiKey: UDSAPMLFQNIXGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4,7-二氢-2-异丙基-1,3-二氧杂卓 、 三溴甲烷 在 sodium hydroxide 、 苄基三乙基氯化铵 作用下， 生成 3,5-Dioxabicyclo[5.1.0]octane, 8,8-dibromo-4-(1-methylethyl)-
  参考文献：
  名称：

  Facial selectivity in the reaction of dihalocarbenes with 2-substituted 4,7-dihydro-1,3-dioxepines

  摘要：

  The dichloro(dibromo)cyclopropanation of conformationally heterogeneous 2-substituted 4,7-dihydro-1,3-dioxepines was found to afford a low selectivity; endo addition on the side of a remote alkyl substitutent is governed by the pi-facial solvation of substrates.

  DOI：

  10.1016/j.mencom.2007.05.013

文献信息

• Facial selectivity in the reaction of dihalocarbenes with 2-substituted 4,7-dihydro-1,3-dioxepines
  作者：Vitaly Yu. Fedorenko、Rustam N. Baryshnikov、Rusalia M. Vafina、Yurii G. Shtyrlin、Evgenii N. Klimovitskii

  DOI：10.1016/j.mencom.2007.05.013

  日期：2007.5

  The dichloro(dibromo)cyclopropanation of conformationally heterogeneous 2-substituted 4,7-dihydro-1,3-dioxepines was found to afford a low selectivity; endo addition on the side of a remote alkyl substitutent is governed by the pi-facial solvation of substrates.