5-Benzylidene-4-thioxothiazolidin-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 5-Benzylidene-4-thioxothiazolidin-2-one
• 英文别名: (5E)-5-benzylidene-4-sulfanylidene-1,3-thiazolidin-2-one
• 化学式: C₁₀H₇NOS₂
• 分子量: 221.3
• InChiKey: ZXBRLSSWWJQDPF-SOFGYWHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  86.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Methods for Screening for Antibiotic Compounds
  申请人：Cheung Ambrose

  公开号：US20120115157A1

  公开（公告）日：2012-05-10

  The present invention is a method for screening drugs for antibiotic activity by screening a drug for activity to disrupt a toxin-antitoxin complex in a bacterial cell.
• Compositions for Treating Bacterial Infections
  申请人：Cheung Ambrose

  公开号：US20120122877A1

  公开（公告）日：2012-05-17

  The present invention is antibiotic compositions having the ability to disrupt a MazEF complex in S. aureus . The compositions also have the ability to inhibit growth of S. aureus and as such are useful as antibiotic compounds.
• METHODS FOR SCREENING ANTIBIOTIC COMPOUNDS
  申请人：Cheung Ambrose

  公开号：US20130295017A1

  公开（公告）日：2013-11-07

  The present invention is a method for screening drugs or antibiotic activity by screening a drug for activity to disrupt a toxin-antitoxin complex in a bacterial cell.
• US9999617B2
  申请人：——

  公开号：US9999617B2

  公开（公告）日：2018-06-19
• [EN] COMPOSITIONS FOR TREATING BACTERIAL INFECTIONS<br/>[FR] COMPOSITIONS POUR TRAITER DES INFECTIONS BACTÉRIENNES
  申请人：DARTMOUTH COLLEGE

  公开号：WO2011002951A1

  公开（公告）日：2011-01-06

  The present invention is antibiotic compositions having the ability to disrupt a MazEF complex in S. aureus. The compositions also have the ability to inhibit growth of S. aureus and as such are useful as antibiotic compounds.