Benzhydryl-carbamic acid butyl ester | 22815-73-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzhydryl-carbamic acid butyl ester
• 英文别名: butyl N-benzhydrylcarbamate
• CAS: 22815-73-2
• 化学式: C₁₈H₂₁NO₂
• 分子量: 283.37
• InChiKey: CKKIQIYBHGMKOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (Benzenesulfonyl-phenyl-methyl)-carbamic acid butyl ester 、 苯硼酸 在 bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate 、 sodium dodecyl-sulfate 、 potassium carbonate 作用下， 以 水 、 甲苯 为溶剂， 反应 0.17h， 以84%的产率得到Benzhydryl-carbamic acid butyl ester
  参考文献：
  名称：

  Rhodium-catalyzed arylation of α-amido sulfones with arylboronic acids in a water–toluene biphasic system

  摘要：

  An efficient method for the synthesis of N-protected diaryl-methyl-amines was developed through a rhodium-catalyzed arylation of alpha-amido sulfones with arylboronic acids in a water-toluene biphasic system. The use of a base combined with a surfactant played a key role in this biphasic reaction. A diverse range of alpha-branched amine derivatives bearing different functional groups were obtained within 10 min under the present conditions. (C) 2010 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2010.09.056

文献信息

• METHOD FOR TREATMENT OF ISOCYANATE RESIDUE, AND METHOD FOR TREATMENT OF CARBONATE
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2518044A1

  公开（公告）日：2012-10-31

  A method for treating an isocyanate residue, which comprises carrying out a thermal decomposition reaction of a carbamate that is produced by the reaction among an amine, urea and/or an N-unsubstituted carbamic acid ester and an alcohol to produce a decomposition solution, separating an isocyanate and the alcohol from the decomposition solution to produce the isocyanate residue, and bringing the isocyanate residue into contact with high-pressure/high-temperature water to decompose the isocyanate residue into an amine; and a method for treating a carbonate, which comprises bringing the carbonate into contact with high-pressure/high-temperature water to decompose the carbonate into an alcohol.

  一种处理异氰酸酯残留物的方法，包括对氨基甲酸酯进行热分解反应，该氨基甲酸酯是由胺、尿素和/或 N-未取代氨基甲酸酯与醇反应生成的，从分解溶液中分离出异氰酸酯和醇，生成异氰酸酯残留物，将异氰酸酯残留物与高压/高温水接触，将异氰酸酯残留物分解成胺；一种处理碳酸盐的方法，包括使碳酸盐与高压/高温水接触，将碳酸盐分解成醇。